Synthetic Approaches to Imidazo[1,2‐a]indole,2,3‐dihydro‐1H‐imidazo[1,2‐a]‐indoles and Benzo[4,5]imidazo[1,2‐a]indole Derivatives: A Comprehensive Review
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DOI: 10.1002/jhet.70026
Abstract: Imidazo[1,2‐a]indoles, 2,3‐dihydro‐1H‐imidazo[1,2‐a]‐indoles and benzo[4,5]imidazo[1,2‐a]indoles are rare yet valuable classes of nitrogen‐containing heterocycles, offering diverse applications in pharmaceutical development and advanced materials research. Despite their potential medicinal applications, efficient synthesis methods for these substances remain limited.… read more here.
Keywords: benzo imidazo; indoles benzo; imidazo indoles; imidazo indole ... See more keywords
MnBr2-Catalyzed Direct and Site-Selective Alkylation of Indoles and Benzo[h]quinoline.
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DOI: 10.1021/acs.orglett.0c01398
Abstract: Manganese-catalyzed regioselective C-H alkylation of indoles and benzo[h]quinoline with a variety of unactivated alkyl iodides is reported. Unlike other Mn-catalyzed C-H functionalization, this protocol does not require a Grignard reagent base and employs a simple… read more here.
Keywords: benzo quinoline; mnbr2 catalyzed; alkylation indoles; indoles benzo ... See more keywords