Genotoxicity of gold nanoparticles functionalized with indolicidin towards Saccharomyces cerevisiae.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of environmental sciences"
DOI: 10.1016/j.jes.2017.04.034
Abstract: The toxic effects of gold nanoparticles surface-functionalized with the antimicrobial peptide indolicidin (AuNPs-indolicidin) towards the yeast Saccharomyces cerevisiae, one of the major eukaryotic model organisms, have been evaluated. Growth and survival, genotoxicity, as measured by… read more here.
Keywords: saccharomyces cerevisiae; gold nanoparticles; indolicidin; genotoxicity ... See more keywords
Binding of Antimicrobial Peptide Indolicidin to DMPC Bilayer Using Replica-Exchange Molecular Dynamics
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DOI: 10.1021/acs.jcim.5c01153
Abstract: Cationic antimicrobial peptides (AMPs) are toxic to microbes, such as bacteria and fungi, and have been increasingly studied as an alternative to traditional antibiotics, in part because AMPs are bactericidal with a minimum risk of… read more here.
Keywords: exchange molecular; indolicidin; dmpc bilayer; molecular dynamics ... See more keywords
Pneumococcal surface protein A (PspA) prevents killing of Streptococcus pneumoniae by indolicidin
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DOI: 10.1038/s41598-024-73564-9
Abstract: Pneumococcal surface protein A (PspA) is an important virulence factor in Streptococcus pneumoniae that binds to lactoferrin and protects the bacterium from the bactericidal action of lactoferricins—cationic peptides released upon lactoferrin proteolysis. The present study… read more here.
Keywords: indolicidin; pspa; pneumococcal surface; surface protein ... See more keywords
Influence of the Polysaccharide Capsule on the Bactericidal Activity of Indolicidin on Streptococcus pneumoniae
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.898815
Abstract: Streptococcus pneumoniae is a pathogen responsible for high morbidity and mortality worldwide. The polysaccharide capsule confers protection against phagocytosis and influences many aspects of pneumococcal pathogenesis. The capsular polysaccharides (CPS) are highly immunogenic and exhibit… read more here.
Keywords: capsule; polysaccharide capsule; indolicidin; streptococcus pneumoniae ... See more keywords