Design, synthesis, molecular modeling, and antimicrobial potential of novel 3-[(1H-pyrazol-3-yl)imino]indolin-2-one derivatives as DNA gyrase inhibitors.
Sign Up to like & getrecommendations! Published in 2021 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202100266
Abstract: A series of 3-[(1H-pyrazol-3-yl)imino]indolin-2-one derivatives were designed using the molecular hybridization method, characterized using different spectroscopic techniques, and evaluated for their in vitro antimicrobial activity. Most of the target compounds demonstrated good to moderate antimicrobial… read more here.
Keywords: one derivatives; pyrazol imino; dna gyrase; indolin one ... See more keywords
Regioselective Cross-Coupling of Isatogens with Boronic Acids to Construct 2,2-Disubstituted Indolin-3-one Derivatives.
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DOI: 10.1021/acs.orglett.1c02808
Abstract: Herein we present a transition-metal-free cross-coupling reaction of isatogens with boronic acids through a 1,4-metalate shift of a boron "ate" complex. This coupling reaction provides a feasible method to deliver valuable 2,2-disubstituted indolin-3-one derivatives with… read more here.
Keywords: boronic acids; one derivatives; disubstituted indolin; indolin one ... See more keywords
Chalcone scaffolds as photofunctional hybrid material of indolin-2-one-functionalized siloxy framework for optical sensing of Cu2+
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DOI: 10.1039/c8nj02884b
Abstract: Owing to their easy approachability and high degree of structural and functional diversity, many multicomponent reactions such as 1,3-dipolar cycloaddition have been a rich source of conjugated π-systems, functionalised chromophores and active molecules. Despite their… read more here.
Keywords: cu2; scaffolds photofunctional; indolin one; photofunctional hybrid ... See more keywords
Theophylline Hydrogen Sulfate: A green and efficient catalyst for synthesis of 3,3-bis(1H-indol-3-yl)indolin-2-one derivatives
Sign Up to like & getrecommendations! Published in 2023 at "Synthetic Communications"
DOI: 10.1080/00397911.2023.2205594
Abstract: Abstract A new green protocol for the synthesis of 3,3-bis(1H-indol-3-yl)indolin-2-one derivatives by reacting isatin with indole in the presence of Theophylline Hydrogen Sulfate as a new solid acid, a highly effective and reusable catalyst. This… read more here.
Keywords: bis indol; catalyst; indolin one; one derivatives ... See more keywords