Sign Up to like & get
recommendations!
0
Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201601645
Abstract: Abstract. Reported herein is a design and synthesis of N-tert-butylsulfinyl-(perfluoro)benzaldimine, and study of its reactivity and stereocontrolling properties in the Mannich addition reactions with in situ generated indolinone derived tertiary enolates. The corresponding products, quaternary…
read more here.
Keywords:
indolin ones;
amino indolin;
quaternary perfluorophenyl;
perfluorophenyl amino ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2020 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2020.03.025
Abstract: Abstract The first HFIP-promoted catalyst-free cascade reactions for the synthesis of biologically relevant 3,3-di(indolyl)indolin-2-ones (27 examples, up to 98% yield) from readily available indoles and isatin derivatives are described. This protocol shows well tolerance of…
read more here.
Keywords:
indolin ones;
hfip promoted;
indolyl indolin;
catalyst free ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b02197
Abstract: Novel methods involving the chemoselective N-H or C-2 arylation for the synthesis of indolo[1,2- a]quinoxalin-6-ones and 2,3'-spirobi[indolin]-2'-ones starting from indole-2-carboxamides were developed. When reactions were carried out using ZnI2 as catalyst and Ag2CO3 as oxidant,…
read more here.
Keywords:
quinoxalin ones;
indolo quinoxalin;
spirobi indolin;
indolin ones ... See more keywords
Photo by nci from unsplash
Sign Up to like & get
recommendations!
1
Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c01198
Abstract: Three crucial anticancer scaffolds, namely indolin-2-one, 1,3,4-thiadiazole, and aziridine, are explored to synthesize virtually screened target molecules based on the c-KIT kinase protein. The stem cell factor receptor c-KIT was selected as target because most…
read more here.
Keywords:
thiadiazole;
cell;
indolin ones;
aziridine ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2019 at "RSC Advances"
DOI: 10.1039/c9ra02569c
Abstract: An efficient palladium-catalyzed intramolecular deacetylative dearomatization reaction of 3-acetoxyindoles is disclosed, affording tetracyclic indolin-3-ones bearing C2-quaternary stereocenters in good yields.
read more here.
Keywords:
intramolecular deacetylative;
tetracyclic indolin;
indolin ones;
catalyzed intramolecular ... See more keywords
Photo from academic.microsoft.com
Sign Up to like & get
recommendations!
0
Published in 2020 at "RSC Advances"
DOI: 10.1039/d0ra05288d
Abstract: Here, we report controlled E–Z isomeric motion of the functionalized 3-benzylidene-indolin-2-ones under various solvents, temperature, light sources, and most importantly effective enhancement of light irradiance in microfluidic photoreactor conditions. Stabilization of the E–Z isomeric motion…
read more here.
Keywords:
indolin ones;
photo;
isomerization benzylidene;
using microfluidic ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2018 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2017.1421181
Abstract: Abstract On account of their significance as apoptosis inducing agents, merging indole and 3-hydrazinoindolin-2-one scaffolds is a logic tactic for designing pro-apoptotic agents. Consequently, 27 hybrids (6a–r, 9a–f and 11a–c) were synthesised and evaluated for…
read more here.
Keywords:
indolin ones;
apoptotic anti;
indolylmethylene hydrazono;
novel indolylmethylene ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2019 at "Journal of Chemical Research"
DOI: 10.1177/1747519819875862
Abstract: A new method for the synthesis of indolin-2-ones has been realized by an I2-promoted oxidative reaction from 1,2,3,3-tetramethyl-3H-indolium iodides. This transformation proceeded smoothly under metal-free and peroxide-free conditions in a cascade manner.
read more here.
Keywords:
indolin ones;
iodine promoted;
promoted one;
one pot ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.821518
Abstract: A novel formal (4 + 1) annulation between N-(o-chloromethyl)aryl amides and 3-chlorooxindoles through in situ generated aza-ortho-QMs with 3-chlorooxindoles is reported for the synthesis of a series of 2,3′-spirobi (indolin)-2′-ones in high yields. Under structured…
read more here.
Keywords:
spirobi indolin;
synthesis spirobi;
ones preliminary;
efficient synthesis ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2020 at "Molecules"
DOI: 10.3390/molecules25133082
Abstract: The subject of this work was the study of thermally and photochemically stimulated Z ↔ E isomerization and hydrazo ↔ azo tautomerism of Z- and E-isomers of isatin arylhydrazones and ((arylamino)methylene)indolin-2-ones and their anions. Using…
read more here.
Keywords:
indolin ones;
methylene indolin;
isatin arylhydrazones;
arylhydrazones arylamino ... See more keywords