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Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.10.066
Abstract: We report structure-activity relationships of 1-arylsulfonyl indoline based benzamides. The benzamide (9) exhibits striking tubulin inhibition with an IC50 value of 1.1 μM, better than that of combretastain A-4 (3), and substantial antiproliferative activity against a…
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Keywords:
new antitubulin;
antitubulin agents;
indoline benzamides;
arylsulfonyl indoline ... See more keywords