Synthesis of the Indolizidine Core of Virosinine A via a Microwave-Promoted Cascade Cyclization Involving Iminyl Radicals.
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DOI: 10.1021/acs.orglett.3c03852
Abstract: The indolizidine core of virosinine A was synthesized by means of a microwave-promoted cascade reaction featuring 5-exo-trig iminyl radical cyclization, thiyl radical elimination, and intramolecular imine alkylation. The resulting bicyclic iminium ion underwent stereoselective reduction… read more here.
Keywords: cyclization; promoted cascade; indolizidine core; core virosinine ... See more keywords