Enantioselective Synthesis of Fluorinated Indolizidinone Derivatives
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DOI: 10.1021/acs.orglett.3c00903
Abstract: The enantioselective synthesis of fluorinated indolizidinone derivatives has been developed. The process involved an enantioselective intramolecular aza-Michael reaction of conjugated amides bearing a pendant α,β-unsaturated ketone moiety, catalyzed by the (S)-TRIP-derived phosphoric acid, followed by… read more here.
Keywords: enantioselective synthesis; synthesis fluorinated; fluorinated indolizidinone; indolizidinone derivatives ... See more keywords