Potential inhibitory effect of indolizine derivatives on the two enzymes: nicotinamide phosphoribosyltransferase and beta lactamase, a molecular dynamics study
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DOI: 10.1007/s00894-017-3363-3
Abstract: Nicotinamide phosphoribosyl-transferases (NAMPT) are enzymes that play a role in targeting cancer metabolism, while beta lactamases are involved in bacterial resistance to beta-lactam antibiotics. Many protein inhibitors exhibit such property which is often correlated with… read more here.
Keywords: molecular dynamics; indolizine derivatives; beta; potential inhibitory ... See more keywords