Condition-controlled selective synthesis of hydroxyl(indolyl)- and bis(indolyl)barbiturates
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Iranian Chemical Society"
DOI: 10.1007/s13738-017-1075-3
Abstract: By combining the structural features of indole and barbituric acid, new hybrid molecules were designed and synthesized. Hydroxy(indolyl)barbiturates and bis(indolyl)barbiturates were selectively prepared via the reaction of indoles with alloxan derivatives in various conditions.Graphical Abstract read more here.
Keywords: bis indolyl; indolyl barbiturates; selective synthesis; controlled selective ... See more keywords
Rare-Earth Metal Complexes Supported by 1,3-Functionalized Indolyl-Based Ligands for Efficient Hydrosilylation of Alkenes.
Sign Up to like & getrecommendations! Published in 2022 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.2c03488
Abstract: Two different 1,3-functionalized indolyl-based proligands 1-(2-C4H7O)CH2-3-(2-tBuC6H5N═CH)C8H5N (HL1) and 1-Me2NCH2CH2-3-(2-iPrC6H5N═CH)C8H5N (HL2) were designed, prepared in high yields, and successfully applied to rare-earth metal chemistry showing different reactivities and different bondings with the central metals. The reactions… read more here.
Keywords: earth; chemistry; earth metal; rare earth ... See more keywords
Energy Transfer Photocatalytic Radical Rearrangement in N-Indolyl Carbonates.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00085
Abstract: A new type of sp3-like N-centered radical has been generated by selective energy transfer catalysis. Upon photoexcitation, homolytic N-O bond cleavage of N-indolyl carbonate in the presence of an Ir complex produced N- and O-centered… read more here.
Keywords: energy; transfer photocatalytic; photocatalytic radical; indolyl ... See more keywords
Gold(I)-Catalyzed Cycloisomerization-Indole Addition Cascade: Synthesis of 3(2H)-Furanone-Incorporated Unsymmetrical 3,3'- Bis(indolyl)methanes.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01845
Abstract: An unprecedented Au(I)-catalyzed domino intramolecular carbonyl-alkyne cyclization/indole addition strategy has been disclosed here. This generalized strategy enables the synthesis of 3(2H)-furanone-incorporated unsymmetrical bis(indolyl)methanes with generation of a stereocenter at the furanone junction from easily accessible… read more here.
Keywords: addition; synthesis; synthesis furanone; indolyl ... See more keywords
Iron(III)-catalyzed tandem annulation of indolyl-substituted p-quinone methides with ynamides for the synthesis of cyclopenta[b]indoles.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc03252j
Abstract: The unique reactivity of indolyl-substituted p-QMs as a new type of two-carbon synthon has been explored for the first time in a novel iron(III)-catalyzed tandem annulation. This (2+2) annulation/retro-4π electrocyclization/imino-Nazarov cyclization cascade reaction is characterized… read more here.
Keywords: catalyzed tandem; annulation; iron iii; indolyl substituted ... See more keywords
Synthesis of 5-aryl-3,3′-bis-indolyl and bis-7-aza-indolyl methanone derivatives from 5-bromo-7-azaindoles via sequential methylenation using microwave irradiation, CAN oxidation, and Suzuki coupling reactions
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DOI: 10.1039/d2ra05849a
Abstract: A catalyst-free and green chemical method has been developed for the methylenation of indole and N-methyl-7-aza indoles with aqueous formaldehyde afforded respective N,N′-dimethyl-3,3′-bis-7-azaindolylmethanes under microwave irradiation in excellent yield. Subsequent oxidation of the products thus… read more here.
Keywords: suzuki coupling; bis; methanone derivatives; methylenation ... See more keywords
Experimental and theoretical studies on SPION@glutathione catalyzed synthesis of indolyl chromene, indolo xanthene, and pyrimido[4,5-b]quinoline
Sign Up to like & getrecommendations! Published in 2018 at "Synthetic Communications"
DOI: 10.1080/00397911.2017.1410893
Abstract: ABSTRACT The potential of glutathione as a catalyst for carbon–oxygen ring cyclization was investigated experimentally as well as computationally. The glutathione molecules were immobilized on superparamagnetic iron-oxide nanoparticle so as to improve the efficiency of… read more here.
Keywords: theoretical studies; experimental theoretical; indolyl; catalyst ... See more keywords
Synthesis and Biological Evaluation of Heterocyclic Substituted Bis(indolyl)methanes.
Sign Up to like & getrecommendations! Published in 2020 at "Current organic synthesis"
DOI: 10.2174/1570179417666200124103400
Abstract: Bis(indolyl)methane derivatives, also considering as metabolites of indole alkaloids, are widely found in nature with a broad range of biological and pharmacological activities. In this work, a series of heterocyclic substituted bis(indolyl)methanes (3a-3p) have been… read more here.
Keywords: indolyl methanes; bis indolyl; substituted bis; heterocyclic substituted ... See more keywords
A Facile and Microwave-assisted Rapid Synthesis of 2-Arylamino-4-(3'-indolyl)- thiazoles as Apoptosis Inducing Cytotoxic Agents.
Sign Up to like & getrecommendations! Published in 2017 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520616666160622095406
Abstract: BACKGROUND AND OBJECTIVE The clinical success of the chemotherapeutic drugs is restricted by the nonspecific toxicity-related adverse side effects. The diverse implication of indoles and thiazoles in medicinal chemistry prompted us to develop a new… read more here.
Keywords: arylamino indolyl; chemistry; indolyl; cancer ... See more keywords
Synthesis and Antimicrobial Activity of Azetidinone and Thiazolidinone Derivatives from Azolylindolyl Schiff's Bases
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DOI: 10.4172/2161-0444.1000478
Abstract: A new class of azolyl indolyl thiazolidinones and azetidinones were prepared from azolyl indolyl Schiff’s bases on reaction with thioglycolic acid and chloroacetyl chloride, respectively under ultrasonication at a frequency of 46 KHz. The chloro… read more here.
Keywords: schiff bases; antimicrobial activity; activity azetidinone; synthesis antimicrobial ... See more keywords