New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains.
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DOI: 10.1016/j.ejmech.2020.112696
Abstract: We designed and synthesized 21 new indolylarylsulfones (IASs) as new HIV-1 NNRTIs. Among these, IAS 12 exhibited a remarkable antiviral activity against single and double mutants (K103N EC50 = read more here.
Keywords: y181c; indolylarylsulfone non; k103n y181c; hiv ... See more keywords