Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells
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DOI: 10.1021/acschembio.5c00751
Abstract: Immunomodulatory imide drugs (IMiDs), including thalidomide, lenalidomide, and pomalidomide, can be used to induce degradation of a protein of interest that is fused to a short degron motif, which often comprises a zinc finger (ZF).… read more here.
Keywords: induce degradation; degradation; orthogonal imid; protein ... See more keywords