2D MoS2 Nanosheets Induce Ferroptosis by Promoting NCOA4-Dependent Ferritinophagy and Inhibiting Ferroportin.
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DOI: 10.1002/smll.202208063
Abstract: The exposure of MoS2 nanosheets can cause cytotoxicity, which causes health risks and affects its medical applications. However, knowledge of the underlying molecular mechanisms remains limited. This study reports that MoS2 nanosheets induces ferroptosis in… read more here.
Keywords: ferritinophagy; nanosheets induce; mos2 nanosheets; ncoa4 dependent ... See more keywords
Artesunate synergizes with sorafenib to induce ferroptosis in hepatocellular carcinoma
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DOI: 10.1038/s41401-020-0478-3
Abstract: Sorafenib is the first-line medication for advanced hepatocellular carcinoma (HCC), but it can only extend limited survival. It is imperative to find a combination strategy to increase sorafenib efficacy. Artesunate is such a preferred candidate,… read more here.
Keywords: hepatocellular carcinoma; induce ferroptosis; treatment; sorafenib ... See more keywords
From iron chelation to overload as a therapeutic strategy to induce ferroptosis in hematologic malignancies
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DOI: 10.1080/16078454.2022.2132362
Abstract: ABSTRACT Objectives Ferroptosis is an iron-dependent, non-apoptotic mode of cell death characterized by excessive accumulation of reactive oxygen species (ROS). It plays an important role in the occurrence, development and treatment of various cancers, but… read more here.
Keywords: hematologic malignancies; iron chelation; ferroptosis hematologic; ferroptosis ... See more keywords