Checkpoint Inhibitors May Induce Myocarditis.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-nb2018-034
Abstract: Myocarditis is a rare but serious side effect that can occur in patients receiving immune checkpoint inhibitors. To better understand the condition, researchers analyzed the symptoms, timing, demographics, and treatment outcomes for 101 patients who… read more here.
Keywords: checkpoint inhibitors; may induce; inhibitors may; induce myocarditis ... See more keywords
Major Group-B Enterovirus populations deleted in the noncoding 5’ region of genomic RNA modulate activation of the type I interferon pathway in cardiomyocytes and induce myocarditis
Sign Up to like & getrecommendations! Published in 2024 at "PLOS Pathogens"
DOI: 10.1371/journal.ppat.1012125
Abstract: Major 5’-terminally deleted (5’TD) RNA forms of group-B coxsackievirus (CVB-5’TD) has been associated with myocarditis in both mice and humans. Although it is known that interferon-β (IFN-β) signaling is critical for an efficient innate immune… read more here.
Keywords: rna forms; induce myocarditis; cvb; activation ... See more keywords