A novel induced aggregation method for intuitionistic fuzzy set and its application in multiple attribute group decision making
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Intelligent Systems"
DOI: 10.1002/int.22009
Abstract: In this paper, by unifying the induced ordered weighted averaging (IOWA) and the weighted average, a novel induced aggregation method for intuitionistic fuzzy set is investigated. More specifically, a new intuitionistic fuzzy (IF) induced aggregation… read more here.
Keywords: induced aggregation; intuitionistic fuzzy; aggregation method; fuzzy ... See more keywords
Shear-induced amyloid formation of IDPs in the brain.
Sign Up to like & getrecommendations! Published in 2019 at "Progress in molecular biology and translational science"
DOI: 10.1016/bs.pmbts.2019.05.008
Abstract: The IDP amyloid β-protein (Aβ) has been both the prime causative suspect and drug development target in the fight against Alzheimer's disease (AD). Unfortunately, all clinical trials against Aβ based on this assumption have failed.… read more here.
Keywords: induced amyloid; shear induced; induced aggregation; amyloid formation ... See more keywords
Design, synthesis and evaluation of scutellarein-O-acetamidoalkylbenzylamines as potential multifunctional agents for the treatment of Alzheimer's disease.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.04.054
Abstract: A series of scutellarein-O-acetamidoalkylbenzylamines derivatives were designed based on a multitarget-directed ligands strategy for the treatment of Alzheimer's disease. Among these compounds, compound T-22 demonstrated excellent acetylcholinesterase inhibitory, moderate inhibitory effects on self-induced Aβ1-42 aggregation,… read more here.
Keywords: alzheimer disease; scutellarein acetamidoalkylbenzylamines; treatment alzheimer; induced aggregation ... See more keywords
Gallic acid: A naturally occurring bifunctional inhibitor of amyloid and metal induced aggregation with possible implication in metal-based therapy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2019.04.059
Abstract: Abstract Metal ions play a vital role in the aggregation of proteins by interfering with their correct folding, thereby affecting protein homeostasis and cell viability, leading to neurodegenerative diseases like Alzheimer's and Parkinson's. Development of… read more here.
Keywords: metal; gallic acid; aggregation; induced aggregation ... See more keywords
Miniaturized Forced Degradation of Therapeutic Proteins and ADCs by Agitation-Induced Aggregation using Orbital Shaking of Microplates.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2021.09.027
Abstract: Microplate-based formulation screening is a powerful approach to identify stabilizing excipients for therapeutic proteins while reducing material requirements. However, this approach is sometimes not representative of studies conducted in relevant container closures. The present study… read more here.
Keywords: orbital shaking; induced aggregation; aggregation; therapeutic proteins ... See more keywords
Radiation-Induced Aggregation and Dehydration of Phytoplankton
Sign Up to like & getrecommendations! Published in 2018 at "High Energy Chemistry"
DOI: 10.1134/s0018143918050053
Abstract: Freshwater microalgae (phytoplankton) are worldwide in their distribution, and they play the most important role in the biological balance of internal water bodies. Because they are unpretentious with respect to ambient environment conditions, the microalgae… read more here.
Keywords: induced aggregation; water; radiation induced; aggregation dehydration ... See more keywords