Incidence and risk estimate of drug‐induced agranulocytosis in Hong Kong Chinese. A population‐based case–control study
Sign Up to like & getrecommendations! Published in 2017 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.4156
Abstract: Drug‐induced agranulocytosis is a rare but life‐threatening adverse drug reaction. Its epidemiology in Chinese is largely unknown. This study aimed to estimate the incidence, mortality, and risk of the drugs associated with agranulocytosis in Hong… read more here.
Keywords: induced agranulocytosis; hong kong; drug induced; drug ... See more keywords
Decreased miR-17-92 cluster expression level in serum and granulocytes preceding onset of antithyroid drug-induced agranulocytosis
Sign Up to like & getrecommendations! Published in 2017 at "Endocrine"
DOI: 10.1007/s12020-017-1481-4
Abstract: PurposeWe aimed to determine changes in miR-17-92 cluster expression in serum and granulocytes from patients with antithyroid drug (ATD)-induced agranulocytosis.MethodsIn this study, real-time polymerase chain reaction (PCR) was used to detect serum miR-17-92 expression levels… read more here.
Keywords: induced agranulocytosis; mir cluster; serum granulocytes; expression ... See more keywords
Emphasis on the early diagnosis of antithyroid drug-induced agranulocytosis: retrospective analysis over 16 years at one Chinese center
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-017-0626-x
Abstract: PurposeAntithyroid drug (ATD)-induced agranulocytosis is a rare but life-threatening adverse drug reaction that occurs in patients during the treatment of Graves’ disease. We aimed to comprehensively examine data for patients with this rare complication and… read more here.
Keywords: induced agranulocytosis; diagnosis; early diagnosis; drug ... See more keywords
SU93 REPLICATION OF TWO INDEPENDENT LOCI IN HLA-DQB1 AND HLA-B CONTRIBUTING TO THE RISK OF CLOZAPINE-INDUCED AGRANULOCYTOSIS
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.282
Abstract: Background The atypical antipsychotic drug clozapine is the only effective drug for treatment-resistant schizophrenia, but also bears the risk of inducing severe adverse drug responses like neutropenia and agranulocytosis. Agranulocytosis and neutropenia occurs in about… read more here.
Keywords: clozapine; induced agranulocytosis; hla dqb1; clozapine induced ... See more keywords
Association of HLA-B and HLA-DRB1 polymorphisms with antithyroid drug-induced agranulocytosis in a Han population from northern China
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DOI: 10.1038/s41598-017-12350-2
Abstract: Antithyroid drug (ATD)-induced agranulocytosis is associated with human leukocyte antigen (HLA) and nearby genes in Southeast Asian and European populations. The susceptibility of the Han population from northern China to ATD-induced agranulocytosis has not been… read more here.
Keywords: induced agranulocytosis; hla drb1; hla; hla hla ... See more keywords
Associations of HLA genotypes with antithyroid drug-induced agranulocytosis: a systematic review and meta-analysis of pharmacogenomics studies.
Sign Up to like & getrecommendations! Published in 2019 at "British journal of clinical pharmacology"
DOI: 10.1111/bcp.13989
Abstract: AIM Antithyroid drug (ATD)-induced agranulocytosis is a life-threatening adverse drug reaction. Previous studies suggested HLA genotypes may play an important role in ATD-induced agranulocytosis. To examine the associations between HLA genotypes and ATD-induced agranulocytosis, we… read more here.
Keywords: hla genotypes; atd induced; hla hla; induced agranulocytosis ... See more keywords
Sepsis and thyroid storm in a patient with methimazole-induced agranulocytosis
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DOI: 10.1136/bcr-2020-235536
Abstract: Paediatric hyperthyroidism cases are mostly caused by Grave’s disease. Thyroid storm is a life-threatening condition seen rarely, in severe thyrotoxicosis, occurring in about 1%–2% of patients with hyperthyroidism. Antithyroid medications and beta-blockers are typically the… read more here.
Keywords: sepsis thyroid; storm; induced agranulocytosis; thyroid storm ... See more keywords
Austrian syndrome, ceftriaxone-induced agranulocytosis and COVID-19
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DOI: 10.1136/bcr-2020-239355
Abstract: We present a case of a 75-year-old woman with Austrian syndrome: pneumonia, meningitis and endocarditis all due to Streptococcus pneumoniae. Transoesophageal echocardiogram demonstrated a large mitral valve vegetation with severe mitral regurgitation. She was treated… read more here.
Keywords: syndrome ceftriaxone; induced agranulocytosis; austrian syndrome; agranulocytosis covid ... See more keywords
Genome-Wide Association Study of Metamizole-Induced Agranulocytosis in European Populations
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DOI: 10.3390/genes11111275
Abstract: Agranulocytosis is a rare yet severe idiosyncratic adverse drug reaction to metamizole, an analgesic widely used in countries such as Switzerland and Germany. Notably, an underlying mechanism has not yet been fully elucidated and no… read more here.
Keywords: genome wide; induced agranulocytosis; metamizole induced; association ... See more keywords
Low-Dose Clozapine-Induced Agranulocytosis in Patients with Movement Disorders—Retrospective Study from India
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Indian Academy of Neurology"
DOI: 10.4103/aian.aian_522_20
Abstract: Annals of Indian Academy of Neurology ¦ Volume 24 ¦ Issue 5 ¦ September-October 2021 831 11. Verma R, Sahu R, Holla V. Neurological manifestations of dengue infection: A review. J Neurol Sci 2014;346:26‐34. 12.… read more here.
Keywords: induced agranulocytosis; clozapine induced; low dose; dose clozapine ... See more keywords