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Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202350384
Abstract: Type I interferon (IFN-I) is the body's first line of defense against pathogen infection. IFN-I can induce cellular antiviral responses and therefore plays a key role in driving antiviral innate and adaptive immunity. Canonical IFN-I…
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Keywords:
antiviral signaling;
ifn;
induced antiviral;
type interferon ... See more keywords
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Published in 2020 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1008461
Abstract: The induction of an interferon-mediated response is the first line of defense against pathogens such as viruses. Yet, the dynamics and extent of interferon alpha (IFNα)-induced antiviral genes vary remarkably and comprise three expression clusters:…
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Keywords:
interferon alpha;
induced antiviral;
ifn induced;
antiviral genes ... See more keywords
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Published in 2022 at "Antibodies"
DOI: 10.3390/antib11030050
Abstract: The multiple mechanisms of action of antiviral monoclonal antibodies (mAbs) have made these molecules a potential therapeutic alternative for treating severe viral infections. In addition to their direct effect on viral propagation, several studies have…
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Keywords:
therapeutic antibodies;
immune responses;
antiviral therapeutic;
immunomodulation induced ... See more keywords