Estrogen inhibits starvation‐induced apoptosis in osteocytes by a redox‐independent process involving association of JNK and glutathione S‐transferase P1‐1
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12216
Abstract: Estrogen deficiency causes bone loss as a result of microdamage, oxidative stress, and osteocyte apoptosis. A relationship between oxidative stress‐induced apoptosis, c‐Jun N‐terminal kinase (JNK) activation, and expression of factors involved in bone remodeling has… read more here.
Keywords: starvation induced; apoptosis; jnk; induced apoptosis ... See more keywords
Dexmedetomidine Attenuates Neuroinflammatory–Induced Apoptosis after Traumatic Brain Injury via Nrf2 signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.50878
Abstract: Dexmedetomidine (DEX) exhibits neuroprotective effects as a multifunctional neuroprotective agent in numerous neurological disorders. However, in traumatic brain injury (TBI), the molecular mechanisms of these neuroprotective effects remain unclear. The present study investigated whether DEX,… read more here.
Keywords: neuroinflammatory induced; brain injury; traumatic brain; induced apoptosis ... See more keywords
TSPAN8 alleviates high glucose‐induced apoptosis and autophagy via targeting mTORC2
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11870
Abstract: TSPAN8 mediates signal transduction from extracellular cues and regulates cell development, activation, growth, and motility. However, whether TSPAN8 is involved in the progression of diabetic nephropathy (DN) remains unclear. This study aimed to explore the… read more here.
Keywords: tspan8; apoptosis; apoptosis cells; high glucose ... See more keywords
Two new alkaloids from Dendrobium nobile Lindl. exhibited neuroprotective activity, and dendrobine alleviated Aβ1−42‐induced apoptosis by inhibiting CDK5 activation in PC12 cells
Sign Up to like & getrecommendations! Published in 2023 at "Drug Development Research"
DOI: 10.1002/ddr.22030
Abstract: Dendrobium nobile Lindl. is registered in the Chinese Pharmacopoeia as a traditional medicine. Phytochemical investigation of the ethanol extract of D. nobile Lindl. stems yielded three alkaloid compounds, including two new compounds dendroxine B (2)… read more here.
Keywords: dendrobine; pc12 cells; nobile lindl; induced apoptosis ... See more keywords
Role of reciprocal interaction between autophagy and endoplasmic reticulum stress in apoptosis of human bronchial epithelial cells induced by cigarette smoke extract
Sign Up to like & getrecommendations! Published in 2019 at "IUBMB Life"
DOI: 10.1002/iub.1937
Abstract: Endoplasmic reticulum stress (ERS)‐induced apoptosis of airway epithelial cells plays an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Furthermore, autophagy is closely related to ERS under apoptosis. Here, this study aimed… read more here.
Keywords: cse induced; apoptosis; induced apoptosis; reciprocal interaction ... See more keywords
Endoplasmic reticulum stress is involved in the T‐2 toxin‐induced apoptosis in goat endometrium epithelial cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3655
Abstract: T‐2 toxin is one of the trichothecene mycotoxins commonly found in animal feed and agricultural products. Ingestion of T‐2 toxin by animals results in acute and chronic diseases, as well as reproductive failure. This study… read more here.
Keywords: epithelial cells; endometrium epithelial; apoptosis; induced apoptosis ... See more keywords
Calcium Uptake via Mitochondrial Uniporter Contributes to Palmitic Acid‐Induced Apoptosis in Mouse Podocytes
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.25930
Abstract: Podocytes are component cells of the glomerular filtration barrier, and their loss by apoptosis is the main cause of proteinuria that leads to diabetic nephropathy (DN). Therefore, insights into podocyte apoptosis mechanism would allow a… read more here.
Keywords: palmitic acid; acid induced; induced apoptosis; acid ... See more keywords
Tumor Necrosis Factor‐α Induced Apoptosis in U937 Cells Promotes Cathepsin D‐Independent Stefin B Degradation
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26152
Abstract: Lysosomal cathepsins were previously found to be involved in tumor necrosis factor‐α (TNFα)‐induced apoptosis. However, there are opposing views regarding their role as either initiators or amplifiers of the signaling cascade as well as the… read more here.
Keywords: degradation; apoptosis u937; apoptosis; induced apoptosis ... See more keywords
Menadione‐induced apoptosis in U937 cells involves Bid cleavage and stefin B degradation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28356
Abstract: Earlier studies showed that the oxidant menadione (MD) induces apoptosis in certain cells and also has anticancer effects. Most of these studies emphasized the role of the mitochondria in this process. However, the engagement of… read more here.
Keywords: apoptosis u937; induced apoptosis; menadione; u937 cells ... See more keywords
Involvement of Bid in the crosstalk between ferroptotic agent‐induced ER stress and TRAIL‐induced apoptosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30863
Abstract: Tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) induces death receptor‐mediated extrinsic apoptosis, specifically in cancer cells, and Bid (BH3‐interacting domain death agonist) plays an important role in TRAIL‐induced apoptosis. Ferroptosis is a newly defined form of… read more here.
Keywords: crosstalk ferroptotic; trail; bid; trail induced ... See more keywords
Polystyrene nanoplastics aggravates lipopolysaccharide‐induced apoptosis in mouse kidney cells by regulating IRE1/XBP1 endoplasmic reticulum stress pathway via oxidative stress
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30913
Abstract: Nanoplastics (NPs) pollution poses a huge threat to the ecosystem and has become one of the environmental pollutants that have attracted much attention. There is increasing evidence that both oxidative stress and endoplasmic reticulum stress… read more here.
Keywords: nps lps; stress; ire1 xbp1; oxidative stress ... See more keywords