MicroRNA-92a serves as a risk factor in sepsis-induced ARDS and regulates apoptosis and cell migration in lipopolysaccharide-induced HPMEC and A549 cell injury.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117957
Abstract: AIMS Sepsis-induced acute respiratory distress syndrome (ARDS) is a common, high mortality complication in intensive care unit (ICU) patients. MicroRNA-92a (miR-92a) plays a role in many diseases, but its association with sepsis-induced ARDS is unclear.… read more here.
Keywords: sepsis; induced ards; migration; cell ... See more keywords
Likelihood of amyloid formation in COVID-19-induced ARDS
Sign Up to like & getrecommendations! Published in 2021 at "Trends in Microbiology"
DOI: 10.1016/j.tim.2021.03.008
Abstract: Severe coronavirus disease 2019 (COVID-19) infection leads to multifactorial acute respiratory distress syndrome (ARDS), with little therapeutic success. The pathophysiology associated with ARDS or post-ARDS is not yet well understood. We hypothesize that amyloid formation… read more here.
Keywords: induced ards; likelihood amyloid; covid; amyloid formation ... See more keywords
Immune dysregulation in COVID-19 induced ARDS in kidney transplant recipients revealed by single-cell RNA sequencing
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DOI: 10.1038/s41598-025-91439-5
Abstract: Since the emergence of COVID-19 at the end of 2019, the disease has led to widespread acute respiratory distress syndrome (ARDS), particularly among kidney transplant recipients (KTRs), who are at increased risk due to long-term… read more here.
Keywords: transplant recipients; kidney transplant; cell; induced ards ... See more keywords
Lung transplant after 6 months on ECMO support for SARS-CoV-2-induced ARDS complicated by severe antibody-mediated rejection
Sign Up to like & getrecommendations! Published in 2021 at "BMJ Open Respiratory Research"
DOI: 10.1136/bmjresp-2021-001036
Abstract: There have been a few reports of successful lung transplantation (LTx) in patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS); however, all reports were with rather short follow-up. Here we present a 62-year-old man without… read more here.
Keywords: cov induced; induced ards; rejection; severe antibody ... See more keywords
Investigating the Intercellular Communication Network of Immune Cell in Acute Respiratory Distress Syndrome with Sepsis
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/4586648
Abstract: Acute respiratory distress syndrome (ARDS) is recognized as a serious public health issue that results in respiratory failure and high mortality rates. The syndrome is characterized by immune cell aggregation, communication, activation, and alveolar epithelial… read more here.
Keywords: sepsis; cell; intercellular communication; communication ... See more keywords
IL-33 Deficiency Attenuates Lung Inflammation by Inducing Th17 Response and Impacting the Th17/Treg Balance in LPS-Induced ARDS Mice via Dendritic Cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/9543083
Abstract: Objectives The characteristic pathophysiological feature of acute respiratory distress syndrome (ARDS) is a dysregulated inflammatory response. T helper 17 (Th17) cells in the lung are inflammatory cells that contribute to pulmonary inflammatory cascades. In addition,… read more here.
Keywords: inflammation; th17 treg; treg balance; lps induced ... See more keywords
Immune characteristics of kidney transplant recipients with acute respiratory distress syndrome induced by COVID-19 at single-cell resolution
Sign Up to like & getrecommendations! Published in 2024 at "Respiratory Research"
DOI: 10.1186/s12931-024-02682-9
Abstract: Background COVID-19-induced acute respiratory distress syndrome (ARDS) can result in tissue damage and multiple organ dysfunction, especially in kidney transplant recipients (KTRs) receiving immunosuppressive drugs. Presently, single-cell research on COVID-19-induced ARDS is considerably advanced, yet… read more here.
Keywords: single cell; analysis; cell; induced ards ... See more keywords
Differences of respiratory mechanics in mechanical ventilation of acute respiratory distress syndrome between patients with COVID-19 and Influenza A
Sign Up to like & getrecommendations! Published in 2024 at "Respiratory Research"
DOI: 10.1186/s12931-024-02730-4
Abstract: Background Whether COVID-19-induced acute respiratory distress syndrome (ARDS) should be approached differently in terms of mechanical ventilation therapy compared to other virus-induced ARDS is debatable. Therefore, we aimed to ascertain whether the respiratory mechanical characteristics… read more here.
Keywords: influenza; mechanics; induced ards; covid induced ... See more keywords
S1PR3 inhibition protects against LPS-induced ARDS by inhibiting NF-κB and improving mitochondrial oxidative phosphorylation
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DOI: 10.1186/s12967-024-05220-9
Abstract: Inflammation and endothelial barrier dysfunction are the major pathophysiological changes in acute respiratory distress syndrome (ARDS). Sphingosine-1-phosphate receptor 3 (S1PR3), a G protein-coupled receptor, has been found to mediate inflammation and endothelial cell (EC) integrity.… read more here.
Keywords: induced ards; s1pr3; s1pr3 inhibition; lps induced ... See more keywords
Pyroptosis-Related Genes as Prognostic Biomarkers and Immune Infiltration Features in Sepsis-Induced ARDS: A Single-Cell and Bulk RNA-Sequencing Analysis
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s539379
Abstract: Background Sepsis-induced acute respiratory distress syndrome (ARDS) is a common and costly syndrome with high mortality and poor prognosis without targeted therapies. Recently, pyroptosis has been demonstrated to be an inflammatory form of programmed cell… read more here.
Keywords: pyroptosis related; analysis; cell; sepsis induced ... See more keywords
Putative Therapeutic Impact of Inflammasome Inhibitors against COVID-19-Induced ARDS.
Sign Up to like & getrecommendations! Published in 2022 at "Current medicinal chemistry"
DOI: 10.2174/0929867329666220906111550
Abstract: Given the importance of COVID-19-induced ARDS, recently, researchers have strived to determine underlying mechanisms involved in the inflammatory responses. In this regard, inflammasomes possess a distinct priority for cytokine storm occurrence and subsequently ARDS progression… read more here.
Keywords: therapeutic impact; inflammasome inhibitors; putative therapeutic; covid induced ... See more keywords