Herpud1 deficiency could reduce amyloid-β40 expression and thereby suppress homocysteine-induced atherosclerosis by blocking the JNK/AP1 pathway
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Physiology and Biochemistry"
DOI: 10.1007/s13105-020-00741-5
Abstract: Homocysteine (Hcy) is considered an independent risk factor for various cardiovascular diseases including atherosclerosis which is associated with lipid metabolism, inflammation, and oxidative stress. Results from our previous study suggested that Hcy-induced atherosclerosis could be… read more here.
Keywords: hcy; induced atherosclerosis; jnk ap1; expression ... See more keywords
Taurine Alleviates Trimethylamine N-Oxide-Induced Atherosclerosis by Regulating Bile Acid Metabolism in ApoE-/- Mice.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c01376
Abstract: Trimethylamine N-oxide (TMAO) widely exists in seafood and is associated with the atherosclerosis progress, but dietary seafood reduced the cardiovascular risk. This intimates that there may be some ingredients in seafood to offset the cardiovascular… read more here.
Keywords: induced atherosclerosis; taurine; trimethylamine oxide; tmao ... See more keywords
Naringenin promotes cell autophagy to improve high-fat-diet-induced atherosclerosis in ApoE-/- mice
Sign Up to like & getrecommendations! Published in 2021 at "Brazilian Journal of Medical and Biological Research"
DOI: 10.1590/1414-431x20209764
Abstract: Naringenin (NAR) is a major flavanone in citrus fruits that has multiple pharmacological attributes such as anticancer and antiatherogenic. This study aims to investigate the mechanism of NAR in high-fat-diet (HFD)-induced atherosclerosis (AS) in apolipoprotein… read more here.
Keywords: mice; high fat; induced atherosclerosis; fat diet ... See more keywords
MicroRNAs as Potential Mediators for Cigarette Smoking Induced Atherosclerosis
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DOI: 10.3390/ijms19041097
Abstract: Smoking increases the risk of atherosclerosis-related events, such as myocardial infarction and ischemic stroke. Recent studies have examined the expression levels of altered microRNAs (miRNAs) in various diseases. The profiles of tissue miRNAs can be… read more here.
Keywords: potential mediators; induced atherosclerosis; high dose; expression ... See more keywords
Insulin-receptor substrate 1 protects against injury in endothelial cell models of ox-LDL-induced atherosclerosis by inhibiting ER stress/oxidative stress-mediated apoptosis and activating the Akt/FoxO1 signaling pathway
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Medicine"
DOI: 10.3892/ijmm.2020.4728
Abstract: Oxidized low-density lipoprotein (ox-LDL)-induced endothelial cell (EC) injury is a risk factor for atherosclerosis. Therefore, the present study aimed to investigate the effects of insulin-receptor substrate 1 (IRS-1) on injury to ox-LDL-exposed ECs. For this… read more here.
Keywords: induced atherosclerosis; apoptosis; foxo1; models ldl ... See more keywords
TET1s deficiency exacerbates oscillatory shear flow-induced atherosclerosis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.69281
Abstract: Background: TET1 has been implicated in regulating inflammation and cardiovascular disease, but a newly discovered short isoform of TET1 (termed TET1s) exhibits higher expression in adult tissues than full-length TET1. However, the precise role of… read more here.
Keywords: expression; tet1; mice; tet1s ... See more keywords