Acute ethanol exposure‐induced autophagy‐mediated cardiac injury via activation of the ROS‐JNK‐Bcl‐2 pathway
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.25934
Abstract: Binge drinking is associated with increased cardiac autophagy, and often triggers heart injury. Given the essential role of autophagy in various cardiac diseases, this study was designed to investigate the role of autophagy in ethanol‐induced… read more here.
Keywords: induced autophagy; ethanol exposure; cardiac injury; ethanol induced ... See more keywords
miR‐20a inhibits hypoxia‐induced autophagy by targeting ATG5/FIP200 in colorectal cancer
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23006
Abstract: Autophagy is a highly conserved lysosome‐mediated protective cellular process in which cytosolic components, including damaged organelles and long‐lived proteins, are cleared. Many studies have shown that autophagy was upregulated in hypoxic regions. However, the precise… read more here.
Keywords: mir 20a; atg5 fip200; cancer; induced autophagy ... See more keywords
Tea polyphenols alleviate tri‐ortho‐cresyl phosphate‐induced autophagy of mouse ovarian granulosa cells
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Toxicology"
DOI: 10.1002/tox.22883
Abstract: Tri‐ortho‐cresyl phosphate (TOCP), a widely used plasticizer in industry, can cause female reproductive damage. Tea polyphenols (TPs) have multiple health effects via inhibiting oxidative stress. However, the reproductive protection of TPs in TOCP‐induced female reproductive… read more here.
Keywords: tps; tocp induced; tocp; induced autophagy ... See more keywords
Endoplasmic reticulum chaperone GRP78 participates in fluoride-induced autophagy in LS8 cells by regulating the IRE1-TRAF2-JNK pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Environmental toxicology"
DOI: 10.1002/tox.23805
Abstract: Fluoride induces endoplasmic reticulum (ER) stress in ameloblasts, which is responsible for enamel mineralization disorder. Fluoride induces autophagy in ameloblasts, but the molecular mechanisms through which ameloblasts respond to fluoride-induced cellular stress and autophagy remain… read more here.
Keywords: chaperone grp78; stress; ls8 cells; fluoride induced ... See more keywords
Protective effect of cadmium-induced autophagy in rat renal mesangial cells
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DOI: 10.1007/s00204-017-2103-x
Abstract: Cadmium damages renal cells, and in particular may cause mesangial cell death by necrosis or apoptosis, depending on exposure conditions in cultured cells. However, there is an uncertainty as to whether Cd2+-induced autophagy can protect… read more here.
Keywords: mesangial cells; renal mesangial; cadmium; cell death ... See more keywords
miR-146a Inhibits dengue-virus-induced autophagy by targeting TRAF6
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Virology"
DOI: 10.1007/s00705-017-3516-9
Abstract: During dengue virus (DENV) infection, the virus manipulates different cellular pathways to assure productive replication, including autophagy. However, it remains unclear how this autophagic process is regulated. Here, we have demonstrated a novel role for… read more here.
Keywords: dengue virus; induced autophagy; traf6; mir 146a ... See more keywords
Short-term waterlogging-induced autophagy in root cells of wheat can inhibit programmed cell death.
Sign Up to like & getrecommendations! Published in 2021 at "Protoplasma"
DOI: 10.1007/s00709-021-01610-8
Abstract: Autophagy is a pathway for the degradation of cytoplasmic components in eukaryotes. In wheat, the mechanism by which autophagy regulates programmed cell death (PCD) is unknown. Here, we demonstrated that short-term waterlogging-induced autophagy inhibited PCD… read more here.
Keywords: root cells; term waterlogging; waterlogging induced; induced autophagy ... See more keywords
LPS-induced autophagy in human dental pulp cells is associated with p38.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of molecular histology"
DOI: 10.1007/s10735-021-10004-2
Abstract: Lipopolysaccharides (LPS), which are components of the cell wall of Gram-negative bacteria, are among the important factors that induce inflammation, including pulpitis. Autophagy in human dental pulp cells (hDPCs) acts as a protective mechanism that… read more here.
Keywords: autophagy human; lps induced; human dental; p38 ... See more keywords
Roles of Autophagy and Protein Kinase C-epsilon in Lipid Metabolism of Nonalcoholic Fatty Liver Cell Models.
Sign Up to like & getrecommendations! Published in 2018 at "Archives of medical research"
DOI: 10.1016/j.arcmed.2018.11.006
Abstract: OBJECTIVE To investigate interaction between autophagy and PKC-ε in lipid metabolism of NAFLD cell models. METHODS HL-7702 cells and SK-HEP-1 cells were cultured in vitro as NAFLD cell models and treated with RAPA to induce autophagy. 3-MA was… read more here.
Keywords: ratio induced; cell models; steatosis; induced autophagy ... See more keywords
Inhibition of endoplasmic reticulum stress-induced autophagy promotes the killing effect of X-rays on sarcoma in mice.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.11.160
Abstract: Endoplasmic reticulum (ER) stress is a conserved cellular process for cells to clear unfolded or misfolded proteins and maintain cell homeostasis under stress conditions. Autophagy may act as a pro-survival strategy to cope with multiple… read more here.
Keywords: sarcoma; endoplasmic reticulum; reticulum stress; stress induced ... See more keywords
The role of ROS-induced autophagy in hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2018 at "Clinics and research in hepatology and gastroenterology"
DOI: 10.1016/j.clinre.2018.01.005
Abstract: Hepatocellular carcinoma (HCC) is a main cause of cancer-related mortality and its etiology is not fully understood. As prominent factors that regulate cellular homeostasis, both reactive oxygen species (ROS) and autophagy are considered to play… read more here.
Keywords: hepatocellular carcinoma; role ros; role; ros induced ... See more keywords