Flavonolignans inhibit ADP induced blood platelets activation and aggregation in whole blood.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2016.12.002
Abstract: Flavonolignans are a group of active chemical compounds presented in the silymarin - a standardized extract obtained from fruits and seeds of Milk thistle (Silybum marianum L. Gaernt.). Since the 70s of the last century,… read more here.
Keywords: blood platelets; flavonolignans inhibit; adp induced; induced blood ... See more keywords
GKT136901 protects primary human brain microvascular endothelial cells against methamphetamine-induced blood-brain barrier dysfunction.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117917
Abstract: AIMS Methamphetamine (METH) is an abused psychostimulant causing public health concern worldwide. While most studies have focused on the neurotoxic effects of METH, METH-induced cerebrovascular dysfunction has recently drawn attention as an important facet of… read more here.
Keywords: blood brain; dysfunction; induced blood; meth induced ... See more keywords
Phosphorylation of EF-P aggravates Streptococcus suis-induced blood–brain barrier damage by enhancing serine protease production
Sign Up to like & getrecommendations! Published in 2025 at "Veterinary Research"
DOI: 10.1186/s13567-025-01612-x
Abstract: Streptococcus suis (S. suis) causes meningitis in humans and pigs. Elongation factor P (EF-P) is an important translation factor that facilitates protein synthesis with polyproline motifs. Posttranslational modification of EF-P is required for its activity… read more here.
Keywords: brain; phosphorylation; induced blood; suis induced ... See more keywords
Endogenous Neural Stem Cell Activation after Low-Intensity Focused Ultrasound-Induced Blood–Brain Barrier Modulation
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065712
Abstract: Endogenous neural stem cells (eNSCs) in the adult brain, which have the potential to self-renew and differentiate into functional, tissue-appropriate cell types, have raised new expectations for neurological disease therapy. Low-intensity focused ultrasound (LIFUS)-induced blood–brain… read more here.
Keywords: barrier modulation; induced blood; blood brain; brain barrier ... See more keywords