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Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27924
Abstract: Destructive bone diseases caused by osteolysis are increasing in incidence. They are characterized by an excessive imbalance of osteoclast formation and activation. During osteolysis, the activation of nuclear factor‐κB (NF‐κB) and mitogen‐activated protein kinase (MAPK)…
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Keywords:
induced osteoclastogenesis;
induced bone;
rankl induced;
bone ... See more keywords
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Published in 2017 at "Current Stem Cell Reports"
DOI: 10.1007/s40778-017-0099-z
Abstract: Purpose of ReviewNormal bone is commonly irradiated during radiation therapy (RT). The true impact of focal radiation on bone tissue remains unclear. The goal of this paper is to present the current understanding of radiation…
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Keywords:
induced bone;
radiation induced;
bone toxicity;
bone ... See more keywords
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Published in 2019 at "Cancer epidemiology"
DOI: 10.1016/j.canep.2019.05.013
Abstract: BACKGROUND This study examined the incidence of skeletal-related events (SRE) among patients with breast cancer (BC)- or prostate cancer (PC)-induced bone metastasis or multiple myeloma (MM) based on a population-based, 12-year healthcare database. METHODS Patients…
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Keywords:
incidence;
induced bone;
year;
metastasis ... See more keywords
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Published in 2018 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2018.06.015
Abstract: Estrogen deficiency and inflammation are known to play important roles in bone metabolism and occurrence of osteoporosis. Monotropein as an iridoid glycoside is reported to decrease estrogen deficiency-induced bone loss and inhibit inflammatory response in…
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Keywords:
lps induced;
monotropein;
induced bone;
bone ... See more keywords
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Published in 2021 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2021.174412
Abstract: Due to the efficacy and tolerability of the available drugs, the current treatment for cancer-induced bone pain (CIBP) is not considered ideal, and new drugs are required for better treatment results. This study investigated whether…
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Keywords:
enhances analgesic;
induced bone;
bone;
cancer ... See more keywords
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Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106202
Abstract: Type 2 diabetes mellitus is often companied with osteoporosis, a process which involves osteoclast activation. In this study, we found tubeimoside I, a natural compound isolated from the Chinese medicinal herb Bolbostemma paniculatum (Maxim) Franquet…
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Keywords:
induced bone;
tubeimoside suppresses;
osteoclast formation;
suppresses diabetes ... See more keywords
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Published in 2021 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2021.108703
Abstract: Cancer-induced bone pain (CIBP) is considered to be one of the most difficult pain conditions to treat. Morphine, an analgesic drug, is widely used in clinical practice, and long-term use of morphine can lead to…
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Keywords:
tolerance;
induced bone;
cancer;
bone pain ... See more keywords
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Published in 2018 at "Redox Biology"
DOI: 10.1016/j.redox.2017.10.011
Abstract: Cancer-induced bone pain (CIBP) is a frequent complication in patients suffering from bone metastases. Previous studies have demonstrated a pivotal role of reactive oxygen species (ROS) in inflammatory and neuropathic pain, and ROS scavengers exhibited…
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Keywords:
cibp;
induced bone;
bone;
cancer induced ... See more keywords
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Published in 2017 at "Scandinavian Journal of Pain"
DOI: 10.1016/j.sjpain.2016.09.011
Abstract: Abstract Background The first line pharmacological treatment of cancer pain is morphine and surrogates but a significant pain relief and a reduction of the side-effects of these compounds makes it necessary to combine them with…
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Keywords:
pl265;
induced bone;
cancer;
receptor ... See more keywords
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Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.3c01322
Abstract: Radiation-induced bone injury management remains a challenge in clinical practice, and there is no effective medicine. Recently, biomass-derived carbon dots (CDs) have attracted attention in biomedical engineering due to the advantages of abundant heteroatoms, low…
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Keywords:
bone injury;
clip3;
radiation;
radiation induced ... See more keywords
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Published in 2023 at "Cell proliferation"
DOI: 10.1111/cpr.13406
Abstract: Collapse of the microvascular system is a prerequisite for radiation-induced bone loss. Since type H vessels, a specific bone vessel subtype surrounded by platelet-derived growth factor receptor β+ (PDGFRβ+ ) perivascular cells (PVCs), has been recently…
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Keywords:
bone;
pdgfr;
bone loss;
radiation ... See more keywords