Articles with "induced bosentan" as a keyword



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Omics-based responses induced by bosentan in human hepatoma HepaRG cell cultures

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Published in 2018 at "Archives of Toxicology"

DOI: 10.1007/s00204-018-2214-z

Abstract: Bosentan is well known to induce cholestatic liver toxicity in humans. The present study was set up to characterize the hepatotoxic effects of this drug at the transcriptomic, proteomic, and metabolomic levels. For this purpose,… read more here.

Keywords: induced bosentan; hepatoma; omics based; human hepatoma ... See more keywords