Cardiac Slc25a49‐Mediated Energy Reprogramming Governs Doxorubicin‐Induced Cardiomyopathy through the G6P–AP‐1–Sln Axis
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202502163
Abstract: Doxorubicin (Dox), a potent antitumor drug, is linked to cardiac toxicity. Few mechanism‐based therapies against cardiotoxicity are available. Dysfunction in mitochondrial energy metabolism contributes to Dox‐induced cardiomyopathy. It is aimed at exploring the association between… read more here.
Keywords: dox induced; energy; energy reprogramming; axis ... See more keywords
Right Ventricular Systolic Dysfunction Predicts Recovery of Left Ventricular Systolic Function and Reduced Quality of Life in Patients With Arrhythmia‐Induced Cardiomyopathy
Sign Up to like & getrecommendations! Published in 2025 at "Clinical Cardiology"
DOI: 10.1002/clc.70070
Abstract: Arrhythmia‐induced cardiomyopathy (AIC) is an underrecognized condition resulting in left ventricular systolic dysfunction (LVSD) that is primarily caused by atrial fibrillation (AFib). The relationship between AIC, right ventricular (RV) function, and quality of life (QoL)… read more here.
Keywords: arrhythmia induced; right ventricular; left ventricular; systolic dysfunction ... See more keywords
Vericiguat improves cardiac remodelling and function in rats with doxorubicin‐induced cardiomyopathy
Sign Up to like & getrecommendations! Published in 2025 at "ESC Heart Failure"
DOI: 10.1002/ehf2.15186
Abstract: Vericiguat, a soluble guanylate cyclase (sGC) stimulator, has been demonstrated effective in improving prognosis of patients with heart failure with reduced ejection fraction. However, there are limited data concerning the effect of vericiguat in patients… read more here.
Keywords: improves cardiac; function rats; vericiguat improves; vericiguat ... See more keywords
Antioxidant, antiapoptotic, and antifibrotic effects of the combination of liposomal resveratrol and carvedilol against doxorubicin‐induced cardiomyopathy in rats
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22492
Abstract: The use of the cytotoxic antibiotic doxorubicin (DOXR) is limited by its dose‐dependent cardiotoxicity. The aim of this study was to evaluate the cardioprotective effect of the combination of carvedilol (CARD) and liposomal resveratrol (LIPO… read more here.
Keywords: combination; cardiomyopathy rats; liposomal resveratrol; doxorubicin ... See more keywords
Infliximab substantially re‐silenced Wnt/β‐catenin signaling and ameliorated doxorubicin‐induced cardiomyopathy in rats
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23312
Abstract: The release of inflammatory cytokines, namely tumor necrosis factor‐α (TNF‐α), plays an important role in the pathogenesis of cardiomyopathy. TNF‐α increases in plasma and in myocardium of heart failure patients. We aimed to investigate the… read more here.
Keywords: rpl ifx; tnf; wnt catenin; induced cardiomyopathy ... See more keywords
Gut microbiota dysbiosis is associated with sepsis‐induced cardiomyopathy in patients: A case‒control study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28267
Abstract: Myocardial injury is a major complication of sepsis and a key factor affecting prognosis. Therefore, early and accurate diagnosis and timely management of sepsis‐induced cardiomyopathy (SICM) are of great significance for the prevention and treatment… read more here.
Keywords: sepsis; associated sepsis; gut microbiota; induced cardiomyopathy ... See more keywords
Arrhythmia induced cardiomyopathy
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Arrhythmia"
DOI: 10.1002/joa3.12094
Abstract: Arrhythmia induced cardiomyopathies (AIC) refer to the collective condition of Arrhythmia, Tachycardia, and ectopy‐induced Cardiomyopathy. Atrial fibrillation (AF) and heart failure (HF) are modern epidemics that often coexist and exacerbate one another. We aim to… read more here.
Keywords: arrhythmia; induced cardiomyopathy; arrhythmia induced;
Risk factors of pacing‐induced cardiomyopathy—Insights from lead position
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Arrhythmia"
DOI: 10.1002/joa3.12712
Abstract: There was no significant difference in the incidence of pacing‐induced cardiomyopathy between right ventricular apex pacing group and OpenCurlyQuote;true CloseCurlyQuote; mid‐right ventricular septum pacing group. The preoperative left ventricular end‐systolic diameter and paced QRS duration… read more here.
Keywords: factors pacing; cardiomyopathy insights; insights lead; induced cardiomyopathy ... See more keywords
Role of Matrix Metalloproteinase-2 in the Development of Cyclophosphamide-Induced Cardiomyopathy
Sign Up to like & getrecommendations! Published in 2018 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-018-4017-x
Abstract: Immunohistochemical assay was employed to determine localization of MMP-2 in cardiomyocytes of WAG rats and changes in MMP-2 expression during modeled cardiomyopathy induced by single intraperitoneal injection of cyclophosphamide (125 mg/kg) alone or in combination… read more here.
Keywords: cardiomyocyte nuclei; cyclophosphamide induced; development cyclophosphamide; cyclophosphamide ... See more keywords
Cardiac resynchronization therapy in cancer patients with chemotherapy-induced cardiomyopathy: a mini review
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DOI: 10.1007/s10741-025-10554-7
Abstract: Chemotherapy-induced cardiomyopathy (CHIC) represents a growing clinical challenge due to the increasing use of cardiotoxic treatments. These therapies can lead to progressive myocardial dysfunction, ultimately resulting in heart failure. Cardiac resynchronization therapy (CRT) has been… read more here.
Keywords: cardiac resynchronization; induced cardiomyopathy; chemotherapy induced; resynchronization therapy ... See more keywords
Attenuation of Sepsis-Induced Cardiomyopathy by Regulation of MicroRNA-23b Is Mediated Through Targeting of MyD88-Mediated NF-κB Activation
Sign Up to like & getrecommendations! Published in 2019 at "Inflammation"
DOI: 10.1007/s10753-019-00958-7
Abstract: Myocardial cell injury or cardiomyopathy is associated with excessive inflammatory response and apoptosis of cardiac myocytes during sepsis. MicroRNA-23b (miR-23b) is a multifunctional miRNA that is considered to regulate immunosuppression in sepsis. The aim of… read more here.
Keywords: sepsis; apoptosis; mir 23b; microrna 23b ... See more keywords