Characterization of an i.p. D-galactose-induced cataract model in rats.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmacological and toxicological methods"
DOI: 10.1016/j.vascn.2020.106891
Abstract: Cataracts have been identified as a main cause of global visual impairment and blindness; in addition, diabetic and aging cataracts are the most common types. The aim of this project was to develop a suitable… read more here.
Keywords: characterization galactose; induced cataract; model; cataract model ... See more keywords
Histone acetyltransferase and Polo-like kinase 3 inhibitors prevent rat galactose-induced cataract
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-56414-x
Abstract: Diabetic cataracts can occur at an early age, causing visual impairment or blindness. The detailed molecular mechanisms of diabetic cataract formation remain incompletely understood, and there is no well-documented prophylactic agent. Galactose-fed rats and ex… read more here.
Keywords: formation; induced cataract; galactose induced; histone acetyltransferase ... See more keywords
Pharmacovigilance of drug-induced cataract using the FDA Adverse Event Reporting System
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-10924-z
Abstract: Cataract is a leading cause of irreversible vision loss, particularly among the elderly, with drug-induced cataract being an underrecognized yet significant contributor to visual impairment. This study investigates the associations between medications and cataract development… read more here.
Keywords: event reporting; cataract; fda adverse; drug induced ... See more keywords
Bioinformatics analysis of microarray data to explore the key genes involved in HSF4 mutation-induced cataract.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of ophthalmology"
DOI: 10.18240/ijo.2018.06.03
Abstract: AIM To reveal the mechanisms of heat-shock transcription factor 4 (HSF4) mutation-induced cataract. METHODS GSE22362, including 3 HSF4-null lens and 3 wild-type lens, was obtained from Gene Expression Omnibus database. After data preprocessing, the differentially… read more here.
Keywords: network; mutation induced; mmu mir; hsf4 mutation ... See more keywords
Therapeutic potential of pupilloplasty combined with phacomulsification and intraocular lens implantation against uveitis-induced cataract.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of ophthalmology"
DOI: 10.18240/ijo.2022.10.06
Abstract: AIM To evaluate the therapeutic effect of pupilloplasty combined with phacomulsification and intraocular lens implantation (PPI) in uveitis-induced cataract. METHODS Total 28 patients with uveitis-induced cataract were enrolled. Within 3mo before the PPI, 7 cases… read more here.
Keywords: uveitis; uveitis induced; intraocular lens; pupilloplasty combined ... See more keywords
Presumed Antihistamine-Induced Cataract in Two Young Males
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmacology and Pharmacotherapeutics"
DOI: 10.4103/jpp.jpp_31_19
Abstract: The use of systemic and topical steroids, amiodarone, and phenothiazines has been established as risk factors for the development of cataract. Antihistaminics are commonly prescribed drugs for a wide range of allergic disorders but have… read more here.
Keywords: induced cataract; presumed antihistamine; two young; young males ... See more keywords