Protective effect of vildagliptin on TNF‐α‐induced chondrocyte senescence
Sign Up to like & getrecommendations! Published in 2019 at "IUBMB Life"
DOI: 10.1002/iub.2049
Abstract: Osteoarthritis (OA) is a common age‐related disorder. Chondrocytes in joint tissue play a critical role in normal articular cartilage function and tissue homeostasis. Local inflammatory cytokine‐induced chondrocyte senescence contributes to the development and progression of… read more here.
Keywords: tnf induced; vildagliptin; senescence; induced chondrocyte ... See more keywords
Circ_0001103 alleviates IL-1β-induced chondrocyte cell injuries by upregulating SIRT1 via targeting miR-375.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical immunology"
DOI: 10.1016/j.clim.2021.108718
Abstract: BACKGROUND Osteoarthritis (OA) is a common inflammatory disease characterized by articular cartilage degeneration and injury. Circular RNAs (circRNAs) are widely involved in the development of human diseases, including OA. The objective of this study was… read more here.
Keywords: sirt1; cell; circ 0001103; mir 375 ... See more keywords
Disturbed Glycometabolism-Induced Chondrocyte Apoptosis Contributes to TMJOA.
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DOI: 10.1111/odi.70011
Abstract: OBJECTIVE Elucidate the mechanism underlying chondrocyte apoptosis induced by abnormal glycometabolism in the early stages of temporomandibular joint osteoarthritis (TMJOA) and identify potential therapeutic targets. DESIGN Established TMJOA model by monosodium iodoacetate(MIA), a direct inhibitor… read more here.
Keywords: glycometabolism; induced chondrocyte; chondrocyte apoptosis; ages rage ... See more keywords