CRISPRthripsis: The Risk of CRISPR/Cas9-induced Chromothripsis in Gene Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Stem Cells Translational Medicine"
DOI: 10.1093/stcltm/szac064
Abstract: Abstract The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 nuclease system has allowed the generation of disease models and the development of therapeutic approaches for many genetic and non-genetic disorders. However, the generation of large… read more here.
Keywords: crispr cas9; induced chromothripsis; cas9 induced; crispr ... See more keywords