PKA, PP1, and DC1 phosphorylation mediate alcohol-induced ciliary dysfunction in Chlamydomonas reinhardtii.
Sign Up to like & getrecommendations! Published in 2019 at "Alcohol"
DOI: 10.1016/j.alcohol.2018.05.001
Abstract: Excessive alcohol consumption impairs mucociliary clearance, in part, by compromising ciliary movement. Our previous study found alcohol reduces ciliary beat frequency in Chlamydomonas through a mechanism that involves the β and γ heavy chains of… read more here.
Keywords: alcohol induced; induced ciliary; alcohol; dc1 phosphorylation ... See more keywords
Lithium-induced ciliary lengthening sparks Arp2/3 complex–dependent endocytosis
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e22-06-0219
Abstract: Ciliary length is highly regulated across cell types, but this tight regulation can be disrupted by lithium, which causes ciliary elongation across cell types and organisms. Here, we use the powerful ciliary model Chlamydomonas reinhardtii… read more here.
Keywords: elongation; lithium; arp2 complex; lithium induced ... See more keywords