Intermittent hypoxia promotes carcinogenesis in azoxymethane and dextran sodium sulfate‐induced colon cancer model
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22957
Abstract: Intermittent hypoxia (IH), a characteristic of obstructive sleep apnea, is known to promote cancer progression and aggressiveness in mouse models. However, little is known regarding the effect of IH on cancer initiation. Here, the effect… read more here.
Keywords: dextran sodium; colon cancer; cancer; induced colon ... See more keywords
Biochemical and molecular aspects of 1,2-dimethylhydrazine (DMH)-induced colon carcinogenesis: a review.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology research"
DOI: 10.1093/toxres/tfaa004
Abstract: 1,2-dimethylhydrazine (DMH) is a member in the class of hydrazines, strong DNA alkylating agent, naturally present in cycads. DMH is widely used as a carcinogen to induce colon cancer in animal models. Exploration of DMH-induced… read more here.
Keywords: induced colon; dmh induced; colon carcinogenesis; colon ... See more keywords
Lactoferrin Inhibits the Development of T2D-Induced Colon Tumors by Regulating the NT5DC3/PI3K/AKT/mTOR Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Foods"
DOI: 10.3390/foods11243956
Abstract: Although increasing evidence shows the association between type 2 diabetes (T2D) and colorectal cancer, the related mechanism remains unclear. This study examined the suppressive effect of lactoferrin (LF) on the development of T2D-induced colon cancer.… read more here.
Keywords: nt5dc3 protein; t2d induced; induced colon; cancer ... See more keywords
The Antioxidant and Antitumor Efficiency of Litophyton sp. Extract in DMH-Induced Colon Cancer in Male Rats
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DOI: 10.3390/life12101470
Abstract: One of the most common tumors to cause death worldwide is colon cancer. This study aims to investigate the antitumor potency of Litophyton sp. methanolic extract (LME) against DMH-induced colon cancer in adult male rats.… read more here.
Keywords: dmh induced; colon cancer; induced colon; colon ... See more keywords
Hesperetin and Capecitabine Abate 1,2 Dimethylhydrazine-Induced Colon Carcinogenesis in Wistar Rats via Suppressing Oxidative Stress and Enhancing Antioxidant, Anti-Inflammatory and Apoptotic Actions
Sign Up to like & getrecommendations! Published in 2023 at "Life"
DOI: 10.3390/life13040984
Abstract: Colon cancer is a major cause of cancer-related death, with significantly increasing rates of incidence worldwide. The current study was designed to evaluate the anti-carcinogenic effects of hesperetin (HES) alone and in combination with capecitabine… read more here.
Keywords: hes cap; colon carcinogenesis; carcinogenesis wistar; induced colon ... See more keywords