Does inflammation mediate behavioural alterations in anaesthesia-induced developmental neurotoxicity?
Sign Up to like & getrecommendations! Published in 2022 at "British journal of anaesthesia"
DOI: 10.1016/j.bja.2021.12.040
Abstract: Anaesthesia exposure early in life potentially impairs neurobehavioural development. A recent study in the Journal investigated the possibility that progesterone mitigates anaesthesia-induced developmental neurotoxicity in neonatal rats exposed to sevoflurane. The novel findings show that… read more here.
Keywords: induced developmental; anaesthesia induced; behavioural alterations; developmental neurotoxicity ... See more keywords
New insights into the mechanism of phthalate-induced developmental effects.
Sign Up to like & getrecommendations! Published in 2018 at "Environmental pollution"
DOI: 10.1016/j.envpol.2018.05.095
Abstract: To investigate the biological pathways involved in phthalate-induced developmental effects, zebrafish embryos were exposed to different concentrations of di-(2-ethylhexyl) (DEHP) and di-butyl phthalate (DBP) for 96 h. Embryonic exposure to DEHP and DBP induced body length… read more here.
Keywords: phthalate induced; developmental effects; phthalate; induced developmental ... See more keywords
The roles of bone morphogenetic protein 2 in perfluorooctanoic acid induced developmental cardiotoxicity and L‐carnitine mediated protection
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2018.05.028
Abstract: &NA; Perfluorooctanoic acid (PFOA), a wide spread environmental pollutant, was associated with developmental cardiotoxicity in chicken embryo, while the underlying molecular mechanism had not been fully elucidated. In the current study, 2 mg/kg (egg weight)… read more here.
Keywords: developmental cardiotoxicity; induced developmental; chicken embryo; bmp2 ... See more keywords
Protective Effect of Chlorogenic Acid and Its Analogues on Lead-Induced Developmental Neurotoxicity Through Modulating Oxidative Stress and Autophagy
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.655549
Abstract: Lead (Pb) is among the deleterious heavy metal and has caused global health concerns due to its tendency to cause a detrimental effect on the development of the central nervous system (CNS). Despite being a… read more here.
Keywords: ccga; induced developmental; effect; neurotoxicity ... See more keywords
Do We Have Viable Protective Strategies against Anesthesia-Induced Developmental Neurotoxicity?
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031128
Abstract: Since its invention, general anesthesia has been an indispensable component of modern surgery. While traditionally considered safe and beneficial in many pathological settings, hundreds of preclinical studies in various animal species have raised concerns about… read more here.
Keywords: anesthesia induced; protective strategies; developmental neurotoxicity; neurotoxicity ... See more keywords