Ethyl pyruvate attenuates ventilation‐induced diaphragm dysfunction through high‐mobility group box‐1 in a murine endotoxaemia model
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.14478
Abstract: Mechanical ventilation (MV) can save the lives of patients with sepsis. However, MV in both animal and human studies has resulted in ventilator‐induced diaphragm dysfunction (VIDD). Sepsis may promote skeletal muscle atrophy in critically ill… read more here.
Keywords: hmgb1; high mobility; group box; diaphragm dysfunction ... See more keywords
State-of-the-Art Opinion Article on Ventilator-Induced Diaphragm Dysfunction: Update on Diagnosis, Clinical Course, and Future Treatment Options
Sign Up to like & getrecommendations! Published in 2022 at "Respiration"
DOI: 10.1159/000527466
Abstract: Evidence from both animal and human studies now supports the development of ventilator-induced diaphragm dysfunction (VIDD) starting as early as 24 h after initiation of mechanical ventilation in the intensive care unit (ICU). However, although… read more here.
Keywords: induced diaphragm; state art; vidd; diaphragm dysfunction ... See more keywords
Mitigation of Ventilator‐induced Diaphragm Atrophy by Transvenous Phrenic Nerve Stimulation
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Respiratory and Critical Care Medicine"
DOI: 10.1164/rccm.201502-0363oc
Abstract: Rationale: Ventilator‐induced diaphragm dysfunction is a significant contributor to weaning difficulty in ventilated critically ill patients. It has been hypothesized that electrically pacing the diaphragm during mechanical ventilation could reduce diaphragm dysfunction. Objectives: We tested… read more here.
Keywords: ventilator induced; ventilated paced; transvenous phrenic; phrenic nerve ... See more keywords
The Signaling Network Resulting in Ventilator‐induced Diaphragm Dysfunction
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Respiratory Cell and Molecular Biology"
DOI: 10.1165/rcmb.2018-0022tr
Abstract: Abstract Mechanical ventilation (MV) is a life‐saving measure for those incapable of adequately ventilating or oxygenating without assistance. Unfortunately, even brief periods of MV result in diaphragm weakness (i.e., ventilator‐induced diaphragm dysfunction [VIDD]) that may… read more here.
Keywords: ventilator induced; dysfunction; diaphragm dysfunction; ventilator ... See more keywords
Altered expression of microRNAs in the rat diaphragm in a model of ventilator-induced diaphragm dysfunction after controlled mechanical ventilation
Sign Up to like & getrecommendations! Published in 2021 at "BMC Genomics"
DOI: 10.1186/s12864-021-07970-y
Abstract: Background Ventilator-induced diaphragm dysfunction (VIDD) is a common complication of life support by mechanical ventilation observed in critical patients in clinical practice and may predispose patients to severe complications such as ventilator-associated pneumonia or ventilator… read more here.
Keywords: ventilator induced; diaphragm dysfunction; expression; ventilator ... See more keywords
Disturbances in Calcium Homeostasis Promotes Skeletal Muscle Atrophy: Lessons From Ventilator-Induced Diaphragm Wasting
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.615351
Abstract: Mechanical ventilation (MV) is often a life-saving intervention for patients in respiratory failure. Unfortunately, a common and undesired consequence of prolonged MV is the development of diaphragmatic atrophy and contractile dysfunction. This MV-induced diaphragmatic weakness… read more here.
Keywords: ventilator induced; muscle; vidd; induced diaphragm ... See more keywords