PWE-024 Effectiveness of anti-inflammatory therapy in immune checkpoint inhibitor-induced diarrhoea/colitis
Sign Up to like & getrecommendations! Published in 2018 at "Gut"
DOI: 10.1136/gutjnl-2018-bsgabstracts.156
Abstract: Introduction Immune checkpoint inhibitors (ICPI), including monoclonal antibodies targeting CLTA-4 (e.g. ipilimumab) and PD-1 (e.g. nivolumab) have transformed the treatment landscape for cancer. However, their success is hampered by the high incidence of immune-mediated toxicity.… read more here.
Keywords: gastroenterology; icpi; colitis; induced diarrhoea ... See more keywords
Role of ErbB1 in the Underlying Mechanism of Lapatinib-Induced Diarrhoea: A Review
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DOI: 10.1155/2022/4165808
Abstract: Lapatinib, an orally administered small-molecule tyrosine kinase inhibitor (SM-TKI), is an effective treatment for ErbB2-positive breast cancer. However, its efficacy as one of the targeted cancer therapies has been hampered by several adverse effects, especially… read more here.
Keywords: review; erbb1; lapatinib; induced diarrhoea ... See more keywords