A genome-wide CRISPR screen identifies HuR as a regulator of apoptosis induced by dsRNA and virus.
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DOI: 10.1242/jcs.258855
Abstract: We performed an unbiased whole-genome CRISPR/Cas9 screen in A549 cells to identify potential regulators involved in cell death triggered by dsRNA. Of several top candidate genes, we identified the RNA binding protein ELAV like protein… read more here.
Keywords: hur; apoptosis; crispr; screen ... See more keywords