Map3k8 controls granulocyte colony-stimulating factor production and neutrophil precursor proliferation in lipopolysaccharide-induced emergency granulopoiesis
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DOI: 10.1038/s41598-017-04538-3
Abstract: Map3k8 has been proposed as a useful target for the treatment of inflammatory diseases. We show here that during lipopolysaccharide-induced emergency granulopoiesis, Map3k8 deficiency strongly impairs the increase in circulating mature (Ly6GhighCD11b+) and immature (Ly6GlowCD11b+)… read more here.
Keywords: map3k8; emergency granulopoiesis; lipopolysaccharide induced; induced emergency ... See more keywords