N ‐Acetylcysteine protects against cobalt chloride‐induced endothelial dysfunction by enhancing glucose‐6‐phosphate dehydrogenase activity
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13449
Abstract: Hypoxia‐induced endothelial dysfunction is known to be involved in the pathogenesis of several vascular diseases. However, it remains unclear whether the pentose phosphate pathway (PPP) is involved in regulating the response of endothelial cells to… read more here.
Keywords: cell; induced endothelial; dysfunction; activity ... See more keywords
The protective effects of azilsartan against oscillatory shear stress‐induced endothelial dysfunction and inflammation are mediated by KLF6
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22766
Abstract: Atherosclerosis is a common cardiovascular disease with high morbidity and mortality. It is reported to be related to oscillatory shear stress (OSS)‐induced endothelial dysfunction and excessive production of inflammatory factors. Azilsartan, a specific antagonist of… read more here.
Keywords: induced endothelial; shear stress; effects azilsartan; oscillatory shear ... See more keywords
Preparation and protective effects of 1,8‐cineole‐loaded self‐microemulsifying drug delivery system on lipopolysaccharide‐induced endothelial injury in mice
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2018.10.012
Abstract: Abstract An optimised 1,8‐cineole‐loaded self‐microemulsifying drug delivery system (CIN‐SMEDDS) with a mean droplet size, polydispersity index, mean zeta potential and encapsulation efficiency of 38.14 ± 1.47 nm, 0.208 ± 0.036, −9.312 ± 1.764 mV and… read more here.
Keywords: endothelial injury; induced endothelial; cin smedds; cineole loaded ... See more keywords
Nanocurcumin and arginine entrapped injectable chitosan hydrogel for restoration of hypoxia induced endothelial dysfunction.
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Biological Macromolecules"
DOI: 10.1016/j.ijbiomac.2020.10.205
Abstract: Abstract Hypoxia is a condition that gradually leads to ischemic damages in organs which is marked by poor tissue perfusion. Depending on the severity of the condition, revascularisation therapies are needed for reducing the risk… read more here.
Keywords: hypoxia; hypoxia induced; induced endothelial; hydrogel ... See more keywords
Proanthocyanidins from the stem bark of Rhus tripartita ameliorate methylgloxal-induced endothelial cell apoptosis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of food and drug analysis"
DOI: 10.1016/j.jfda.2019.02.002
Abstract: In traditional Arabian medicine, the Rhus tripartita plant (family Anacardiaceae) has been used to treat inflammatory conditions. Although Rhus extracts have been reported for their cardioprotective effects, information regarding their active principle compounds remains insufficient.… read more here.
Keywords: rhus tripartita; endothelial cell; stem bark; apoptosis ... See more keywords
Pioglitazone and/or irbesartan ameliorate COPD-induced endothelial dysfunction in side stream cigarette smoke-exposed mice model.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119706
Abstract: AIMS Cigarette smoking (CS) is the main cause of chronic obstructive pulmonary disease (COPD). Endothelial dysfunction is related to the severity of pulmonary disease in COPD. This study aimed to evaluate the effectiveness of single… read more here.
Keywords: induced endothelial; copd induced; copd; pio irb ... See more keywords
THE PIVOTAL ROLE OF NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 2 IN DIABETES-INDUCED ENDOTHELIAL DYSFUNCTION.
Sign Up to like & getrecommendations! Published in 2019 at "Pharmacological research"
DOI: 10.1016/j.phrs.2019.104601
Abstract: Endothelial dysfunction (ED) is a key event in the onset and progression of vascular complications associated with diabetes. Regulation of endothelial function and the underlying signaling mechanisms in the progression of diabetes-induced vascular complications have… read more here.
Keywords: induced endothelial; role; factor; diabetes induced ... See more keywords
Interleukin-35 inhibits lipopolysaccharide-induced endothelial cell activation by downregulating inflammation and apoptosis.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2021.112784
Abstract: Inflammation is an essential factor contributing to sepsis-induced endothelial cell (EC) activation. Interleukin-35 (IL-35) is an anti-inflammatory/immunosuppressive cytokine that exerts protective effects on many inflammatory diseases. In this study, we investigated the effects of IL-35… read more here.
Keywords: induced endothelial; endothelial cell; inflammation; cell activation ... See more keywords
Endoplasmic Reticulum Peroxynitrite Fluctuations in Hypoxia-Induced Endothelial Injury and Sepsis with a Two-Photon Fluorescence Probe.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c05040
Abstract: Sepsis is a serious systemic inflammatory disease that frequently results in death. Early diagnosis and timely targeted interventions could improve the therapeutic effect. Recent work has revealed that the reactive oxygen species (ROS) in the… read more here.
Keywords: endothelial injury; endoplasmic reticulum; sepsis; hypoxia induced ... See more keywords
Vitexin inhibits APEX1 to counteract the flow-induced endothelial inflammation.
Sign Up to like & getrecommendations! Published in 2021 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2115158118
Abstract: Vascular endothelial cells are exposed to shear stresses with disturbed vs. laminar flow patterns, which lead to proinflammatory vs. antiinflammatory phenotypes, respectively. Effective treatment against endothelial inflammation and the consequent atherogenesis requires the identification of… read more here.
Keywords: induced endothelial; endothelial inflammation; vitexin; flow induced ... See more keywords
Mechanisms of leptin-induced endothelial dysfunction
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Nephrology and Hypertension"
DOI: 10.1097/mnh.0000000000000867
Abstract: Purpose of review Endothelial dysfunction is a major risk factor for many cardiovascular diseases, notably hypertension. Obesity increases the risk of endothelial dysfunction in association with increasing production of the adipokine leptin. Preclinical studies have… read more here.
Keywords: mechanisms leptin; induced endothelial; dysfunction; endothelial dysfunction ... See more keywords