Protective Effect of Luminal Uric Acid Against Indomethacin-Induced Enteropathy: Role of Antioxidant Effect and Gut Microbiota
Sign Up to like & getrecommendations! Published in 2021 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-021-06848-z
Abstract: Uric acid (UA) has anti- and pro-inflammatory properties. We previously revealed that elevated serum UA levels provide protection against murine small intestinal injury probably via luminal UA secreted in the small intestine. Luminal UA may… read more here.
Keywords: microbiota; induced enteropathy; indomethacin induced; effect ... See more keywords
Utility of intestinal ultrasound in the diagnosis and short-term follow-up of non-steroidal anti-inflammatory drug-induced enteropathy
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DOI: 10.1007/s11739-019-02161-w
Abstract: Due to their anti-inflammatory and analgesic effects, nonsteroidal anti-inflammatory drugs (NSAIDs) are largely used in clinical practice even if they could be associated with severe gastrointestinal adverse effects, such as peptic ulcer disease, bleeding and… read more here.
Keywords: anti inflammatory; bowel; intestinal ultrasound; induced enteropathy ... See more keywords
Exacerbation of non‐steroidal anti‐inflammatory drug‐induced enteropathy in C‐C chemokine receptor type 7‐deficient mice
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.15868
Abstract: Non‐steroidal anti‐inflammatory drugs (NSAIDs) induce intestinal enteropathy and the pathophysiology is related to immune‐mediated mechanisms. We aimed to investigate the role of C‐C chemokine receptor type 7 (CCR7) which regulates immune cell migration in NSAID‐induced… read more here.
Keywords: induced enteropathy; chemokine receptor; steroidal anti; anti inflammatory ... See more keywords
Olmesartan-induced enteropathy
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DOI: 10.1136/bcr-2018-224411
Abstract: Olmesartan-induced enteropathy (OIE) typically presents with a constellation of signs and symptoms including chronic diarrhoea, weight loss and villous atrophy on biopsy. We describe a 68-year-old Caucasian woman with a history of hypothyroidism and hypertension… read more here.
Keywords: induced enteropathy; olmesartan induced; diarrhoea;
Atorvastatin Inhibits Endothelial PAI-1-Mediated Monocyte Migration and Alleviates Radiation-Induced Enteropathy
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DOI: 10.3390/ijms22041828
Abstract: Intestinal injury is observed in cancer patients after radiotherapy and in individuals exposed to radiation after a nuclear accident. Radiation disrupts normal vascular homeostasis in the gastrointestinal system by inducing endothelial damage and senescence. Despite… read more here.
Keywords: pai; radiation induced; induced enteropathy; atorvastatin ... See more keywords
Metformin Protects the Intestinal Barrier by Activating Goblet Cell Maturation and Epithelial Proliferation in Radiation-Induced Enteropathy
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DOI: 10.3390/ijms23115929
Abstract: Radiotherapy or accidental exposure to high-dose radiation can cause severe damage to healthy organs. The gastrointestinal (GI) tract is a radiation-sensitive organ of the body. The intestinal barrier is the first line of defense in… read more here.
Keywords: induced enteropathy; intestinal barrier; radiation; radiation induced ... See more keywords