Epigenetic Markers and Microbiota/Metabolite-Induced Epigenetic Modifications in the Pathogenesis of Obesity, Metabolic Syndrome, Type 2 Diabetes, and Non-alcoholic Fatty Liver Disease
Sign Up to like & getrecommendations! Published in 2019 at "Current Diabetes Reports"
DOI: 10.1007/s11892-019-1151-4
Abstract: Purpose of ReviewThe metabolic syndrome is a pathological state in which one of the key components is insulin resistance. A wide spectrum of body compartments is involved in its pathophysiology. Genetic and environmental factors such… read more here.
Keywords: induced epigenetic; epigenetic modifications; non alcoholic; disease ... See more keywords
HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response.
Sign Up to like & getrecommendations! Published in 2019 at "Gastroenterology"
DOI: 10.1053/j.gastro.2019.02.038
Abstract: BACKGROUND & AIMS Chronic hepatitis C virus (HCV) infection is an important risk factor for hepatocellular carcinoma (HCC). Despite effective antiviral therapies, the risk for HCC is decreased but not eliminated after a sustained virologic… read more here.
Keywords: hcv induced; induced epigenetic; risk; infection ... See more keywords
Lamarck rises from his grave: parental environment‐induced epigenetic inheritance in model organisms and humans
Sign Up to like & getrecommendations! Published in 2017 at "Biological Reviews"
DOI: 10.1111/brv.12322
Abstract: Organisms can change their physiological/behavioural traits to adapt and survive in changed environments. However, whether these acquired traits can be inherited across generations through non‐genetic alterations has been a topic of debate for over a… read more here.
Keywords: induced epigenetic; environment induced; parental environment; epigenetic inheritance ... See more keywords
Mitochondrial-induced epigenetic modifications: from biology to clinical translation.
Sign Up to like & getrecommendations! Published in 2020 at "Current pharmaceutical design"
DOI: 10.2174/1381612826666200826165735
Abstract: Mitochondria are maternally inherited semi-autonomous organelles that play a central role in redox balance, energy metabolism, control of integrated stress responses, and cellular homeostasis. The molecular communication between mitochondria and the nucleus is intricate and… read more here.
Keywords: induced epigenetic; epigenetic modifications; mitochondrial induced; biology ... See more keywords
Caloric restriction induced epigenetic effects on aging
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.1079920
Abstract: Aging is the subject of many studies, facilitating the discovery of many interventions. Epigenetic influences numerous life processes by regulating gene expression and also plays a crucial role in aging regulation. Increasing data suggests that… read more here.
Keywords: caloric restriction; restriction; aging caloric; restriction induced ... See more keywords
Transmission of stimulus-induced epigenetic changes through cell division is coupled to continuous transcription factor activity
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1129577
Abstract: Trained immunity, or innate immune memory, has been attributed to the long-term retention of stimulus-induced histone post-translational modifications (PTMs) following clearance of the initial stimulus. Yet, it remains unknown how this epigenetic memory can persist… read more here.
Keywords: stimulus induced; cell division; stimulus; induced epigenetic ... See more keywords
Acute Stress-Induced Epigenetic Modulations and Their Potential Protective Role Toward Depression
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2018.00184
Abstract: Psychiatric disorders entail maladaptive processes impairing individuals’ ability to appropriately interface with environment. Among them, depression is characterized by diverse debilitating symptoms including hopelessness and anhedonia, dramatically impacting the propensity to live a social and… read more here.
Keywords: induced epigenetic; depression; stress induced; acute stress ... See more keywords