Mechanical stress promotes angiogenesis through fibroblast exosomes.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.04.159
Abstract: BACKGROUND Mechanical stress can induce multiple functional changes in vascular endothelial cells, including proliferation, differentiation, and migration. Furthermore, human fibroblasts are susceptible to external mechanical stress. In this work, we investigated whether mechanical stress can… read more here.
Keywords: mechanical stress; angiogenesis; exosomes fibroblasts; static stretching ... See more keywords
Role of hypoxia-induced exosomes in tumor biology
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Cancer"
DOI: 10.1186/s12943-018-0869-y
Abstract: PurposeHypoxia is a major regulator of angiogenesis and always influences the release of exosomes in various types of tumors. The present review aimed to assess the role of hypoxia-induced exosomes in the tumor biology.MethodsThe relevant… read more here.
Keywords: role hypoxia; biology; hypoxia; exosomes tumor ... See more keywords
Microbially-Induced Exosomes from Dendritic Cells Promote Paracrine Immune Senescence: Novel Mechanism of Bone Degenerative Disease in Mice
Sign Up to like & getrecommendations! Published in 2023 at "Aging and Disease"
DOI: 10.14336/ad.2022.0623
Abstract: As the aging population grows, chronic age-related bone degenerative diseases become more prevalent and severe. One such disease, periodontitis (PD), rises to 70.1% prevalence in Americans 65 years and older. PD has been linked to… read more here.
Keywords: bone degenerative; disease; senescence; induced exosomes ... See more keywords
The therapeutical effects of damage-specific stress induced exosomes on the cisplatin nephrotoxicity IN VIVO.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular and cellular probes"
DOI: 10.2139/ssrn.4117260
Abstract: Cisplatin is one of the metal containing drugs for the solid cancer treatments. However, its side-effects limit its application in the cancer treatment. Stem cell therapy is a promising treatment for the tissue damage caused… read more here.
Keywords: stress; damage; cisplatin; stress induced ... See more keywords
The Effect of Hypoxia-Induced Exosomes on Anti-Tumor Immunity and Its Implication for Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.915985
Abstract: Hypoxia is a critical feature of solid tumors and is considered to be a key factor in promoting tumorigenesis and progression. Beyond inducing metabolic reprogramming of tumor cells to adapt to the hypoxia tumor microenvironment… read more here.
Keywords: hypoxia induced; anti tumor; immunotherapy; induced exosomes ... See more keywords