Activation of microglia and macrophages in the circumventricular organs of the mouse brain during TLR2-induced fever and sickness responses
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2019.576973
Abstract: Toll-like receptor 2 (TLR2) recognizes cell wall components from Gram-positive bacteria. Until now, however, little has been known about the significance of brain TLR2 in controlling inflammation and thermoregulatory responses during systemic Gram-positive bacterial infection.… read more here.
Keywords: microglia macrophages; brain tlr2; induced fever; tlr2 ... See more keywords
The Neurokinin-1 Receptor Contributes to the Early Phase of Lipopolysaccharide-Induced Fever via Stimulation of Peripheral Cyclooxygenase-2 Protein Expression in Mice
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.00166
Abstract: Neurokinin (NK) signaling is involved in various inflammatory processes. A common manifestation of systemic inflammation is fever, which is usually induced in animal models with the administration of bacterial lipopolysaccharide (LPS). A role for the… read more here.
Keywords: induced fever; receptor contributes; nk1 receptor; expression ... See more keywords