Cyclosporine‐induced gingival overgrowth—Review
Sign Up to like & getrecommendations! Published in 2022 at "Dermatologic Therapy"
DOI: 10.1111/dth.15912
Abstract: Drug‐induced gingival overgrowth (DIGO) is an undesirable effect resulting from the therapy of one of the three groups of drugs: phenytoin, calcium channel blockers, and cyclosporine A (CsA). It is caused by a fibrous overgrowth… read more here.
Keywords: gingival overgrowth; cyclosporine induced; induced gingival; review ... See more keywords
Dental plaque–induced gingival conditions
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Periodontology"
DOI: 10.1111/jcpe.12937
Abstract: OBJECTIVE This review proposes revisions to the current classification system for gingival diseases and provides a rationale for how it differs from the 1999 classification system. IMPORTANCE Gingival inflammation in response to bacterial plaque accumulation… read more here.
Keywords: induced gingival; inflammation; gingival conditions; dental plaque ... See more keywords
Cyclosporine A-induced gingival overgrowth in renal transplant patients accompanied by epithelial-to-mesenchymal transition.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of periodontal research"
DOI: 10.1111/jre.13115
Abstract: OBJECTIVE To investigate the association between the prevalence of cyclosporin A-induced gingival overgrowth and the expression of the epithelial-to-mesenchymal transition factors in the gingival tissues of renal transplant patients. BACKGROUND Gingival overgrowth (GO) is a… read more here.
Keywords: gingival overgrowth; transplant patients; induced gingival; csa ... See more keywords
Phenytoin-induced gingival overgrowth caused by death receptor pathway malfunction.
Sign Up to like & getrecommendations! Published in 2017 at "Oral diseases"
DOI: 10.1111/odi.12651
Abstract: OBJECTIVE In this study, we investigated the role of phenytoin (PHT) in death receptor-induced apoptosis of gingival fibroblasts to clarify the mechanism of PHT-induced gingival overgrowth. METHODS Human gingival fibroblasts were cultured to semiconfluence and… read more here.
Keywords: pht; death receptor; induced gingival; gingival fibroblasts ... See more keywords
Therapeutic potential of proteasome inhibitors for dihydropyridine-induced gingival overgrowth.
Sign Up to like & getrecommendations! Published in 2019 at "Oral diseases"
DOI: 10.1111/odi.13260
Abstract: OBJECTIVES NF-κB plays a crucial role in collagen overproduction in dihydropyridine-induced gingival overgrowth (DIGO) fibroblasts. We aim to investigate the role of the kappa B (IκB) kinase (IKK)-NF-κB pathway and downstream collagen type I (Col… read more here.
Keywords: proteasome inhibitors; induced gingival; digo cells; dihydropyridine induced ... See more keywords
Role of IL-6 and STAT3 signaling in dihydropyridine-induced gingival overgrowth fibroblasts.
Sign Up to like & getrecommendations! Published in 2020 at "Oral diseases"
DOI: 10.1111/odi.13724
Abstract: OBJECTIVES This study analyzed the role of the interleukin (IL)-6/signal transducer and activator of transcription 3 (STAT3) pathway in dihydropyridine-induced gingival overgrowth (DIGO) fibroblasts. MATERIALS AND METHODS Tissue samples were obtained through surgical dissection from… read more here.
Keywords: induced gingival; stat3; digo; role ... See more keywords
Photodynamic therapy for the successful management of cyclosporine-related gum hypertrophy: A novel therapeutic option
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Public Health Research"
DOI: 10.1177/22799036221116177
Abstract: Background: Drug-induced gingival overgrowth is associated with the intake of three classes of drugs: anticonvulsants, immunosuppressants, and calcium channel blockers. It is clinically characterized by hyperplasia of the gingival connective tissue which appears edematous, bloody,… read more here.
Keywords: drug induced; induced gingival; therapy; case ... See more keywords
Distribution of biopsied non plaque-induced gingival lesions in a Chilean population according to the classification of periodontal diseases
Sign Up to like & getrecommendations! Published in 2018 at "BMC Oral Health"
DOI: 10.1186/s12903-018-0567-6
Abstract: BackgroundMany gingival lesions are not induced by plaque. The aim of this study was to analyze the frequency of biopsied non-plaque-induced gingival lesions (NPIGL) in a Chilean population.MethodsOne thousand twelve cases of biopsied gingival lesions… read more here.
Keywords: classification; induced gingival; non plaque; gingival lesions ... See more keywords
Calcium Channel Blocker-induced Gingival Overgrowth
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DOI: 10.2169/internalmedicine.0852-18
Abstract: A 69-year-old man was admitted to the hospital with bacterial pneumonia. He had previously been diagnosed with mild hypertension and treated with oral calcium channel blockers for six months. He denied any history of an… read more here.
Keywords: calcium channel; channel; induced gingival; gingival overgrowth ... See more keywords
Systematic review of cyclosporin A-induced gingival overgrowth and genetic predisposition.
Sign Up to like & getrecommendations! Published in 2017 at "Quintessence international"
DOI: 10.3290/j.qi.a38120
Abstract: OBJECTIVE This systematic review aimed to investigate the influence of gene polymorphisms on the development of gingival overgrowth in renal transplant patients treated with cyclosporin A. METHOD AND MATERIALS Electronic and hand literature searches were… read more here.
Keywords: systematic review; cyclosporin induced; induced gingival; gingival overgrowth ... See more keywords
Is dental plaque the only etiological factor in Amlodipine induced gingival overgrowth? A systematic review of evidence
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical and Experimental Dentistry"
DOI: 10.4317/jced.54715
Abstract: Background Amlodipine, a dihydropyridine calcium channel blocker (CCB) is commonly prescribed for cardiovascular conditions. Its administration may produce an uncommon adverse oral manifestation, the gingival overgrowth (GO). Lately, there has been an increase in the… read more here.
Keywords: systematic review; induced gingival; amlodipine induced; amlodipine ... See more keywords