Ethanol Extract of Lycopodium serratum Thunb. Attenuates Lipopolysaccharide-Induced C6 Glioma Cells Migration via Matrix Metalloproteinase-9 Expression
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DOI: 10.1007/s11655-017-2923-9
Abstract: ObjectiveTo elucidate how ethanol extract of L. serratum (ELS) could exert anti-migratory effects on glioma with the suppression of nuclear factor kappa B (NF-κB) downstream pathway.MethodsCell viability of ELS on C6 glioma was detected by… read more here.
Keywords: induced glioma; glioma; ethanol extract; migration ... See more keywords
Hypoxia-Induced Glioma-Derived Exosomal miRNA-199a-3p Promotes Ischemic Injury of Peritumoral Neurons by Inhibiting the mTOR Pathway
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DOI: 10.1155/2020/5609637
Abstract: The underlying molecular mechanisms that the hypoxic microenvironment could aggravate neuronal injury are still not clear. In this study, we hypothesized that the exosomes, exosomal miRNAs, and the mTOR signaling pathway might be involved in… read more here.
Keywords: induced glioma; glioma; mtor; injury ... See more keywords
A Novel Orthotopic Patient-Derived Xenograft Model of Radiation-Induced Glioma Following Medulloblastoma
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DOI: 10.3390/cancers12102937
Abstract: Simple Summary Radiation-induced glioma (RIG) is a highly aggressive brain cancer arising as a consequence of radiation therapy, for which there is currently no effective treatment. In order to test new drugs in the hope… read more here.
Keywords: induced glioma; radiation induced; radiation; model ... See more keywords
Endoplasmic Reticulum Stress Contributes to Indomethacin-Induced Glioma Apoptosis
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DOI: 10.3390/ijms21020557
Abstract: The dormancy of cellular apoptotic machinery has been highlighted as a crucial factor in therapeutic resistance, recurrence, and poor prognosis in patients with malignancy, such as malignant glioma. Increasing evidence indicates that nonsteroidal anti-inflammatory drugs… read more here.
Keywords: induced glioma; glioma; apoptosis; endoplasmic reticulum ... See more keywords