3-Deoxyglucosone interferes with insulin signaling and attenuates insulin action on glucose-induced GLP-1 secretion in the enteroendocrine L cell line STC-1
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Biology Reports"
DOI: 10.1007/s11033-019-04926-0
Abstract: Maintenance of glucose homeostasis is reciprocally regulated by insulin and glucagon-like peptide-1 (GLP-1). We previously reported that GLP-1 secretion in response to an oral glucose load was impaired following an administration of 3-deoxyglucosone (3DG), an independent… read more here.
Keywords: insulin; stc; induced glp; glp secretion ... See more keywords
βHB inhibits glucose-induced GLP-1 secretion in GLUTag and human jejunal enteroids.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of molecular endocrinology"
DOI: 10.1530/jme-22-0115
Abstract: Ingestion of nutrients stimulates incretin secretion from the enteroendocrine cells (EECs) of the epithelial layer of the gut. Glucagon-like peptide-1 (GLP-1) is one of these incretins that stimulates postprandial insulin release and signals satiety to… read more here.
Keywords: glp secretion; glucose induced; glutag; human jejunal ... See more keywords
The Sensory Mechanisms of Nutrient-Induced GLP-1 Secretion
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DOI: 10.3390/metabo12050420
Abstract: The enteroendocrine system of the gut regulates energy homeostasis through the release of hormones. Of the gut-derived hormones, GLP-1 is particularly interesting, as analogs of the hormone have proven to be highly effective for the… read more here.
Keywords: glp secretion; mechanisms nutrient; secretion; nutrient induced ... See more keywords
Dihydromyricetin Enhances Exercise-Induced GLP-1 Elevation through Stimulating cAMP and Inhibiting DPP-4
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DOI: 10.3390/nu14214583
Abstract: The purpose of this study was to examine whether endogenous GLP-1 (glucagon-like peptide-1) could respond to exercise training in mice, as well as whether dihydromyricetin (DHM) supplementation could enhance GLP-1 levels in response to exercise… read more here.
Keywords: gut microbiota; camp; exercise induced; glp levels ... See more keywords