In silico identification of potential inhibitor for TP53-induced glycolysis and apoptosis regulator in head and neck squamous cell carcinoma
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DOI: 10.1007/s13205-021-02665-3
Abstract: Head and neck squamous cell carcinoma (HNSCC) is the six most common cancer globally and most common cancer in men in India. The metabolic regulation is highly altered and is considered as a hall mark… read more here.
Keywords: glycolysis apoptosis; tp53 induced; apoptosis regulator; induced glycolysis ... See more keywords
The Expression of TP53-Induced Glycolysis and Apoptosis Regulator (TIGAR) Can Be Controlled by the Antioxidant Orchestrator NRF2 in Human Carcinoma Cells
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DOI: 10.3390/ijms23031905
Abstract: Hyperactivation of the KEAP1-NRF2 axis is a common molecular trait in carcinomas from different origin. The transcriptional program induced by NRF2 involves antioxidant and metabolic genes that render cancer cells more capable of dealing with… read more here.
Keywords: induced glycolysis; expression; tp53 induced; regulator ... See more keywords