Interferon-induced GTPases orchestrate host cell-autonomous defence against bacterial pathogens
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical Society Transactions"
DOI: 10.1042/bst20200900
Abstract: Interferon (IFN)-induced guanosine triphosphate hydrolysing enzymes (GTPases) have been identified as cornerstones of IFN-mediated cell-autonomous defence. Upon IFN stimulation, these GTPases are highly expressed in various host cells, where they orchestrate anti-microbial activities against a… read more here.
Keywords: autonomous defence; bacterial pathogens; cell autonomous; induced gtpases ... See more keywords
Role of interferon-induced GTPases in leishmaniasis
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0010093
Abstract: Leishmaniasis continues to be a major health problem worldwide. The efficacy of reported vaccines is poor, and there is no safe and cost-effective treatment, partly because the mechanisms of the disease are not fully understood.… read more here.
Keywords: gtpases leishmaniasis; induced gtpases; role; interferon induced ... See more keywords