Protective effect of neurotensin receptor-1 agonist PD 149163 against lipopolysaccharide-induced gut toxicity in mice.
Sign Up to like & getrecommendations! Published in 2021 at "Drug and chemical toxicology"
DOI: 10.1080/01480545.2021.1954698
Abstract: The interaction between neuroendocrine and immune components of the gut maintains the organism's physical and psychological health. Its disruption may reflect in disease conditions such as inflammatory bowel disease (IBD) and mental illness. The lipopolysaccharide… read more here.
Keywords: neurotensin receptor; protective effect; agonist 149163; toxicity ... See more keywords
Indole-3-Propionic Acid as a Potential Therapeutic Agent for Sepsis-Induced Gut Microbiota Disturbance
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DOI: 10.1128/spectrum.00125-22
Abstract: The role of gut microbiota in the pathophysiology of sepsis is gaining increasing attention and developing effective and safe sepsis therapies targeting intestinal microorganisms is promising. Given the safety of probiotic supplementation or fecal microbiota… read more here.
Keywords: sepsis; intestinal microbiota; microbiota; gut microbiota ... See more keywords
Cathelicidin-WA Protects Against LPS-Induced Gut Damage Through Enhancing Survival and Function of Intestinal Stem Cells
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.685363
Abstract: Preservation of intestinal stem cells (ISCs) plays a critical role in initiating epithelial regeneration after intestinal injury. Cathelicidin peptides have been shown to participate in regulating intestinal damage repair. However, it is not known how… read more here.
Keywords: lps induced; intestinal stem; damage; function ... See more keywords
Pain and Opioid-Induced Gut Microbial Dysbiosis
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DOI: 10.3390/biomedicines10081815
Abstract: Opioid-induced dysbiosis (OID) is a specific condition describing the consequences of opioid use on the bacterial composition of the gut. Opioids have been shown to affect the epithelial barrier in the gut and modulate inflammatory… read more here.
Keywords: opioid induced; dysbiosis; pain opioid; induced gut ... See more keywords
Diet-Induced Gut Barrier Dysfunction Is Exacerbated in Mice Lacking Cannabinoid 1 Receptors in the Intestinal Epithelium
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DOI: 10.3390/ijms231810549
Abstract: The gut barrier provides protection from pathogens and its function is compromised in diet-induced obesity (DIO). The endocannabinoid system in the gut is dysregulated in DIO and participates in gut barrier function; however, whether its… read more here.
Keywords: diet induced; induced gut; gut barrier; intestinal epithelium ... See more keywords