Aloe Emodin Alleviates Radiation‐Induced Heart Disease via Blocking P4HB Lactylation and Mitigating Kynurenine Metabolic Disruption
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202406026
Abstract: Aloe emodin is an anthraquinone of traditional Chinese medicine monomer, which plays a protective action in cardiovascular diseases. However, the regulatory mechanisms of aloe emodin in the protection of radiation‐induced heart damage (RIHD) are unclear.… read more here.
Keywords: induced heart; radiation induced; lactylation; aloe emodin ... See more keywords
Canine Model of Pacing-Induced Heart Failure.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8597-5_24
Abstract: Tachypacing-induced heart failure is a well-established large animal model that recapitulates numerous pathophysiological, structural and molecular features of dilated cardiomyopathy and, more in general, of end-stage congestive heart failure. The left or the right ventricle… read more here.
Keywords: heart; canine model; induced heart; heart failure ... See more keywords
Pathomechanisms and therapeutic opportunities in radiation-induced heart disease: from bench to bedside
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Research in Cardiology"
DOI: 10.1007/s00392-021-01809-y
Abstract: Cancer management has undergone significant improvements, which led to increased long-term survival rates among cancer patients. Radiotherapy (RT) has an important role in the treatment of thoracic tumors, including breast, lung, and esophageal cancer, or… read more here.
Keywords: radiation induced; heart disease; heart; induced heart ... See more keywords
AHR/ROS-mediated mitochondria apoptosis contributes to benzo[a]pyrene-induced heart defects and the protective effects of resveratrol.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology"
DOI: 10.1016/j.tox.2021.152965
Abstract: Benzo[a]pyrene (BaP), a prototypical polycyclic aromatic hydrocarbon, is widely present in the environment. BaP-induced heart defects have been frequently reported, but the underlying molecular mechanisms remain elusive. Here, we found that BaP increased heart malformations… read more here.
Keywords: heart; apoptosis; induced heart; bap induced ... See more keywords
AUTOIMMUNE INDUCED HEART BLOCK
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(18)33152-8
Abstract: Rheumatoid arthritis (RA) is a very common autoimmune disease, affecting around 1% of the general population. Although not always clinically apparent, it can manifest in the form of cardiovascular pathology in 50% of affected patients(1).… read more here.
Keywords: cardiology; autoimmune induced; pathology; induced heart ... See more keywords
Differences in Radiation-Induced Heart Dysfunction in Male Versus Female Rats.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of radiation biology"
DOI: 10.1080/09553002.2023.2194404
Abstract: PURPOSE Radiation therapy remains part of the standard of care for breast, lung, and esophageal cancers. While radiotherapy improves local control and survival, radiation-induced heart dysfunction is a common side effect of thoracic radiotherapy. Cardiovascular… read more here.
Keywords: induced heart; female rats; dysfunction; heart ... See more keywords
Ameliorative Effect of Dangguibuxue Decoction against Cyclophosphamide-Induced Heart Injury in Mice
Sign Up to like & getrecommendations! Published in 2018 at "BioMed Research International"
DOI: 10.1155/2018/8503109
Abstract: Dangguibuxue decoction (DBD), a kind of Chinese herbal medicine, has been widely used to treat blood deficiency disease in China. In this experiment, we studied the effects of the Dangguibuxue decoction (DBD) on the myocardial… read more here.
Keywords: heart; dangguibuxue decoction; induced heart; mice ... See more keywords
Hdac8 Inhibitor Alleviates Transverse Aortic Constriction-Induced Heart Failure in Mice by Downregulating Ace1
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/6227330
Abstract: Background Heart failure is characterized by activation of the renin-angiotensin-aldosterone system, which is involved in the regulation of cardiac hypertrophy and hypertension. Recently, we reported that Hdac8 inhibition alleviates isoproterenol-induced and angiotensin II-induced cardiac hypertrophy… read more here.
Keywords: induced heart; hdac8; heart failure; heart ... See more keywords
The Impact of Procyanidin Extracted from Crataegus azarolus on Rats with Induced Heart Failure.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2022.68.9.28
Abstract: This study aimed to investigate the possible use of Procyanidin extracted from Crataegus azarolus in the treatment of induced heart failure in rats. Thirty-six male rats were randomly assigned to three groups; the first two… read more here.
Keywords: induced heart; procyanidin extracted; heart failure; heart ... See more keywords
Protective Role of Shenmai Injection on Radiation-Induced Heart Injury
Sign Up to like & getrecommendations! Published in 2023 at "Radiation Research"
DOI: 10.1667/rade-20-00279.1
Abstract: Radiation-induced heart injury (RIHI) limits the dose delivery of radiotherapy for thoracic cancer. Shenmai injection (SMI) is reported to have potential cytoprotective properties and is commonly used in cardiovascular diseases. So, we aimed to investigate… read more here.
Keywords: induced heart; heart injury; radiation; radiation induced ... See more keywords
Machine Learning Using a Single-Lead ECG to Identify Patients With Atrial Fibrillation-Induced Heart Failure
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.812719
Abstract: Aims Atrial fibrillation (AF) and heart failure often co-exist. Early identification of AF patients at risk for AF-induced heart failure (AF-HF) is desirable to reduce both morbidity and mortality as well as health care costs.… read more here.
Keywords: induced heart; atrial fibrillation; single lead; heart ... See more keywords