Mitochondrial-targeted ubiquinone alleviates concanavalin A-induced hepatitis via immune modulation.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106518
Abstract: BACKGROUND Despite knowledge regarding the effects of antioxidants in ameliorating oxidative damage, evidence concerning their effects on activated immune cells is lacking. Here, a concanavalin A (Con A)-induced hepatitis mouse model was used to investigate… read more here.
Keywords: modulation; hepatitis; con; mitochondrial targeted ... See more keywords
Potential therapeutic effect of thymoquinone and/or bee pollen on fluvastatin-induced hepatitis in rats.
Sign Up to like & getrecommendations! Published in 2021 at "Scientific reports"
DOI: 10.1038/s41598-021-95342-7
Abstract: Hepatitis is one of earlier, but serious, signs of liver damage. High doses of statins for a long time can induce hepatitis. This study aimed to evaluate and compare the therapeutic potential of thymoquinone (TQ)… read more here.
Keywords: fluvastatin induced; bee pollen; hepatitis; pollen fluvastatin ... See more keywords
Compromise or not? A case report of successful treatment of pembrolizumab‐induced hepatitis in a patient with non‐small cell lung cancer with low‐dose methylprednisolone and bicyclol
Sign Up to like & getrecommendations! Published in 2020 at "Thoracic Cancer"
DOI: 10.1111/1759-7714.13463
Abstract: Pembrolizumab, an anti‐programmed cell death protein 1 (PD‐1) antibody, has been shown to improve survival in patients with non‐small cell lung cancer (NSCLC) with high expression of programmed death‐ligand 1 (PD‐L1). Corticosteroids are the mainstay… read more here.
Keywords: low dose; hepatitis; case; pembrolizumab ... See more keywords
γδ T cells are indispensable for interleukin‐23‐mediated protection against Concanavalin A‐induced hepatitis in hepatitis B virus transgenic mice
Sign Up to like & getrecommendations! Published in 2017 at "Immunology"
DOI: 10.1111/imm.12712
Abstract: Hepatitis B virus surface antigen (HBsAg) carriers are highly susceptible to liver injury triggered by environmental biochemical stimulation. Previously, we have reported an inverse correlation between γδ T cells and liver damage in patients with… read more here.
Keywords: hbs; hepatitis; liver damage; hepatitis virus ... See more keywords
NOD-Like Receptor Protein 3 Inflammasome-Dependent IL-1β Accelerated ConA-Induced Hepatitis
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.00758
Abstract: Autoimmune hepatitis (AIH) is a progressive inflammatory disorders of unknown etiology, characterized by immune-mediated destruction of hepatocytes and massive production of cytokines. Interleukin-1β is a pleiotropic proinflammatory cytokine and well known to be critical in… read more here.
Keywords: cona induced; hepatitis; inflammasome dependent; cona ... See more keywords
CP-25 exerts a protective effect against ConA-induced hepatitis via regulating inflammation and immune response
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1041671
Abstract: Hepatitis is a complex multifactorial pathological disorder, which can eventually lead to liver failure and even potentially be life threatening. Paeoniflorin-6′-O-benzene sulfonate (CP-25) has proven to have critical anti-inflammatory effects in arthritis. However, the effects… read more here.
Keywords: inflammation; exerts protective; hepatitis; induced hepatitis ... See more keywords