HMGB1 gene silencing inhibits neuroinflammation via down-regulation of NF-κB signaling in primary hippocampal neurons induced by Aβ25-35.
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DOI: 10.1016/j.intimp.2018.12.027
Abstract: High mobility group box 1 protein (HMGB1) is potentially triggered by Aβ oligomers and other sterile injuries, and is a non-histone DNA binding nuclear protein with roles in neural development and neurodegeneration, which contribute to… read more here.
Keywords: hmgb1; hippocampal neurons; neuroinflammation; hmgb1 gene ... See more keywords