Propentofylline decreases hypothalamic astrogliosis induced by hypercaloric diet in the rat.
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DOI: 10.1590/0004-282x20180019
Abstract: Obesity is associated with a chronic and low-grade inflammatory response in the hypothalamus, where astrogliosis occurs with the upregulation of the astrocyte structural protein GFAP. As propentofylline (PPF) has inhibitory effects on astrocyte and microglial… read more here.
Keywords: hypothalamic astrogliosis; rats receiving; induced hypercaloric; astrogliosis ... See more keywords