Rechallenge After Oxaliplatin-Induced Hypersensitivity Reactions.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.7136
Abstract: This cohort study assesses the outcome of oxaliplatin desensitization for patients with gastrointestinal cancers who experienced hypersensitivity reactions after oxaliplatin infusion. read more here.
Keywords: oncology; rechallenge oxaliplatin; oxaliplatin induced; hypersensitivity ... See more keywords
Drug‐induced hypersensitivity syndrome and eosinophils in skin biopsy in a patient with pancytopenia
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26742
Abstract: A 76-year-old man with acute myeloid leukemia (AML) presented to the Emergency Department with fever, a pruritic diffuse rash, and worsening painful oral ulcerations. Four days prior, the patient was initiated on low-dose cytarabine (LDAC)… read more here.
Keywords: drug induced; induced hypersensitivity; drug; hypersensitivity syndrome ... See more keywords
Targeting enkephalins and pituitary adenylate cyclase-activating polypeptide (PACAP) in migraine
Sign Up to like & getrecommendations! Published in 2022 at "Brain"
DOI: 10.1093/brain/awac260
Abstract: modulating PACAP-38-induced hypersensitivity between the RAMP1 deficient and wild-type mice. Furthermore, the humanized monoclonal CGRP antibody (ALD405) did not prevent PACAP-38-induced hypersensitivity in wild-type mice. In addition, the study found that the TRPA1 channel was… read more here.
Keywords: targeting enkephalins; migraine; pacap induced; pacap ... See more keywords
Drug‐induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms following nivolumab and ipilimumab in a pediatric patient with melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Dermatology"
DOI: 10.1111/pde.14940
Abstract: Drug‐induced hypersensitivity syndrome (DIHS) is a type of severe cutaneous adverse reaction (SCAR). DIHS typically occurs 2–6 weeks after initiation of the offending medication. We report a case of DIHS in a pediatric patient undergoing… read more here.
Keywords: drug induced; hypersensitivity syndrome; pediatric patient; drug ... See more keywords
Methotrexate-induced Hypersensitivity Pneumonitis appearing after 30 years of use: a case report
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Medical Case Reports"
DOI: 10.1186/s13256-017-1333-0
Abstract: BackgroundMethotrexate has been implicated in a variety of lung complications, one of which is hypersensitivity pneumonitis. Hypersensitivity pneumonitis most often occurs within the first year of starting low-dose orally administered methotrexate. We present a case… read more here.
Keywords: hypersensitivity pneumonitis; methotrexate; induced hypersensitivity; case ... See more keywords
Immunologic Effects of Beryllium Exposure
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DOI: 10.1513/annalsats.201707-573mg
Abstract: Abstract Metal‐induced hypersensitivity is driven by T‐cell sensitization to metal ions. Although numerous metals are associated with the development of diffuse parenchymal lung disease, beryllium‐induced hypersensitivity is the best‐studied to date. This review focuses on… read more here.
Keywords: induced hypersensitivity; effects beryllium; immunologic effects; beryllium exposure ... See more keywords
Drug-induced hypersensitivity syndrome after initiation of darunavir and raltegravir.
Sign Up to like & getrecommendations! Published in 2017 at "Revista da Sociedade Brasileira de Medicina Tropical"
DOI: 10.1590/0037-8682-0373-2016
Abstract: A 38-year-old HIV-infected African-Brazilian woman on virologic treatment failure presented with a 5-day history of fever, malaise, and a cutaneous eruption that started on the face. She appeared ill and icteric (Figures A/C), which she… read more here.
Keywords: induced hypersensitivity; figure; drug induced; drug ... See more keywords
Atypical, Levetiracetam-induced Hypersensitivity Syndrome Complicated by Fulminant Liver Failure in a Patient Undergoing Hemodialysis
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DOI: 10.2169/internalmedicine.8985-21
Abstract: A 59-year-old man undergoing hemodialysis was administered levetiracetam, after which he developed a systemic rash, high fever, severe liver dysfunction, and leukocytopenia with reactivation of human herpes virus 6. Atypical drug-induced hypersensitivity (DIHS) was diagnosed,… read more here.
Keywords: undergoing hemodialysis; liver failure; fulminant liver; levetiracetam ... See more keywords
Oxaliplatin-induced hypersensitivity reactions: risk factors and management.
Sign Up to like & getrecommendations! Published in 2023 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202303_31801
Abstract: OBJECTIVE Chemotherapy-related adverse reactions have been steadily increasing in recent years. In patients who develop oxaliplatin-induced hypersensitivity reactions (HSRs), prognosis and quality of life are adversely affected. Proper management of cancer patients enables them to… read more here.
Keywords: risk factors; management; oxaliplatin induced; induced hypersensitivity ... See more keywords
Dysregulation of dopamine neurotransmission in the nucleus accumbens in immobilization-induced hypersensitivity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.988178
Abstract: Cast immobilization causes sensory hypersensitivity, which is also a symptom of neuropathic pain and chronic pain. However, the mechanisms underlying immobilization-induced hypersensitivity remain unclear. The present study investigated the role of dopamine neurotransmission in the… read more here.
Keywords: immobilization; immobilization induced; dopamine; cast immobilization ... See more keywords